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ProteomicsApplication of integrated omics in aseptic loosening of prostheses after hip replacement
Aseptic loosening (AL) of artificial hip joints is the most common complication following hip replacement surgery. In the present study, second-generation high-throughput sequencing and mass spectrometry techniques were used to detect differentially expressed genes, proteins and metabolites in sampl...
ORGANISM(S): Homo Sapiens 
2024-12-14 | PXD058886 |
ProteomicsThe aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK
The activity of 5’-adenosine monophosphate-activated protein kinase (AMPK) is inversely correlated with the cellular availability of glucose. When glucose levels are low, the glycolytic enzyme aldolase is not bound to fructose-1,6-bisphosphate (FBP) and, instead, signals to activate lysosomal AMPK. ...
ORGANISM(S): Oryctolagus Cuniculus 
2022-08-10 | PXD035968 |
UnknownPrevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study.
Not available
S-EPMC7880913 | biostudies-literature
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S-EPMC12492304 | biostudies-literature
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S-EPMC11187765 | biostudies-literature
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S-EPMC7556338 | biostudies-literature
UnknownDexamethasone in Hospitalized Patients with Covid-19.
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S-EPMC7383595 | biostudies-literature
UnknownAzithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
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S-EPMC7884931 | biostudies-literature
UnknownCasirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial.
Not available
S-EPMC8830904 | biostudies-literature
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