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ProteomicsHuh-7 exosomes and HBV
Hepatitis B virus (HBV) infection could cause hepatitis, liver cirrhosis and hepatocellular carcinoma. HBV-mediated pathogenesis is only partially understood, but X protein (HBx) reportedly possesses oncogenic potential. Exosomes are small membrane vesicles with diverse functions released by various...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080794 | MassIVE
ProteomicsTNFAIP8-containing exosomes from injured tubular epithelial cells inhibit fibroblast apoptosis in fibrotic kidney
Tubule-derived exosomes play an essential role in mediating population of fibroblasts and renal fibrogenesis through shuttling TNFAIP8 to block p53 pathway
ORGANISM(S): Homo Sapiens 
2022-06-16 | PXD034545 |
ProteomicsHuh-7 exosomes and HBV - Quantitative Proteomic Analysis of Exosome Protein Content Changes Induced by Hepatitis B Virus in Huh-7 Cells Using SILAC Labeling and LC-MS/MS
Hepatitis B virus (HBV) infection could cause hepatitis, liver cirrhosis and hepatocellular carcinoma. HBV-mediated pathogenesis is only partially understood, but X protein (HBx) reportedly possesses oncogenic potential. Exosomes are small membrane vesicles with diverse functions released by various...
ORGANISM(S): Homo sapiens (Human) 
2014-10-09 | PXD001339 | Pride
Hbx Exosome Hepatitis b virus 
ProteomicsCircular RNA circBNC2 regulates epithelial cell G2-M arrest to prevent fibrotic maladaptive repair
Epithelial cells arrested in G2/M phase of the cell cycle after injury is a key checkpoint for determining the wound-healing to either normal cell proliferation or fibrosis. The mechanism that regulates the fibrogenic response after injury is not well understood. Here, we identified a kidney- and li...
ORGANISM(S): Homo Sapiens 
2022-04-18 | PXD033284 |
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