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TranscriptomicsA comprehensive synthetic genetic interaction network governing yeast histone acetylation and deacetylation
Histone acetylation and deacetylation are among the principal mechanisms by which chromatin is regulated during transcription, DNA silencing, and DNA repair. We analyzed patterns of genetic interactions uncovered during comprehensive genome-wide analyses in yeast to probe how histone acetyltransfera...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-11 | E-GEOD-9771 | biostudies-arrayexpress
UnknownSOCS3 Genetic Polymorphism Is Associated With Clinical Features and Prognosis of Hepatocellular Carcinoma Patients Receiving Hepatectomy.
Not available
S-EPMC4616756 | biostudies-literature
ProteomicsAmino Acids Downregulate SIRT4 to Detoxify Ammonia through the Urea Cycle
Ammonia production via glutamate dehydrogenase is inhibited by SIRT4, a sirtuin that displays both amidase and non-amidase activities. The processes underlying the regulation of ammonia removal by amino acids remain unclear. Here, we report that SIRT4 acts as a decarbamylase that responds to amino a...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-29 | PXD037101 | Pride
Carbamylation Liver Mice 
MetabolomicsGlobal metabolomics of fireflies (Coleoptera: Lampyridae) explore metabolic adaptation to fresh water in insects

Aquatic insects are well-adapted to freshwater environments, but metabolic mechanisms of such adaptations, particularly to primary environmental factors (e.g., hypoxia, water pressure, dark light and abundant microbes), are poorly known. Most firefly species (Coleoptera: Lampyridae) are terrestri...

2022-10-03 | MTBLS4987 | MetaboLights
UnknownThe mRNA-lncRNA landscape of multiple tissues uncovers key regulators and molecular pathways that underlie heterosis for feed intake and efficiency in laying chickens.
Not available
S-EPMC10559425 | biostudies-literature
ProteomicsPhenylalanine Impairs Insulin Signaling and Inhibits Glucose Uptake Through Modification of IRβ
Whether amino acids act on cellular insulin signaling remains unclear, given that increased circulating amino acid levels are associated with the onset of type 2 diabetes (T2D). Here, we report that phenylalanine modifies insulin receptor beta (IRβ) and inactivates insulin signaling and glucose upta...
ORGANISM(S): Homo sapiens (Human) 
2022-07-22 | PXD035076 | Pride
Type 2 diabetes Phenylalanylation Insulin receptor 
Unknown{Bis[2-(dicyclo-hexyl-phosphino)-phen-yl]methyl-silyl-κP,Si,P'}chloridopalladium(II).
Not available
S-EPMC2959264 | biostudies-literature
UnknownActivated spinal astrocytes contribute to the later phase of carrageenan-induced prostatitis pain.
Not available
S-EPMC6814979 | biostudies-literature
UnknownBoron-lead multiple bonds in the PbB2O- and PbB3O2- clusters.
Not available
S-EPMC9814552 | biostudies-literature
UnknownThe Proteome Landscape of Human Placentas for Monochorionic Twins with Selective Intrauterine Growth Restriction.
Not available
S-EPMC11082409 | biostudies-literature
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