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ProteomicsTMT-based quantitative proteomics analysis reveals the attenuated replication mechanism of Newcastle disease virus caused by nuclear localization signal mutation in viral matrix protein
Nuclear localization of cytoplasmic RNA virus proteins mediated by intrinsic nuclear localization signal (NLS) plays essential roles in successful virus replication. We previously reported that NLS mutation in the matrix (M) protein obviously attenuates the replication and pathogenicity of Newcastle...
ORGANISM(S): Cricetidae 
2020-05-22 | PXD018098 | Pride
Newcastle disease virus  matrix protein  nuclear localization signal  nucleocytoplasmic trafficking  tmt  quantitative proteomics 
ProteomicsIonizable polymeric micelles (IPMs) for efficient siRNA delivery
Lipid nanoparticles (LNPs) are widely used for nucleic acid delivery but face challenges like limited targeting and accelerated blood clearance. We design three ionizable oligo-mers (IOs) that, with PLA-PEG, form Ionizable Polymeric Micelles (IPMs), a potential siRNA delivery system, which can achie...
ORGANISM(S): Mus musculus (Mouse) 
2024-11-21 | PXD057444 | Pride
Hsp47 Protein corona Hmgb1 Hepatic fibrosis Fibroblast activation protein inhibitor (fapi) Nucleic acid delivery Ionizable polymeric micelles (ipms) Hepatic stellate cells 
ProteomicsEnrichment strategy for searching missing protein
Enrichment strategy for searching missing protein is a project under the guidance of Chromosome-Centric Human Proteome Project (C-HPP). We developed systematical enrichment strategies for revealing the existence of MPs including low molecular weight (LMW), membrane proteins, post-translational modif...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-06-12 | MSV000083957 | MassIVE
MetabolomicsLipidomic profiling reveals distinct differences in plasma lipid composition in healthy, prediabetic and type 2 diabetic individuals

The relationship between dyslipidemia and type 2 diabetes mellitus (T2D) has been extensively reported, but the global lipid profiles, especially in the East Asia population, associated with the development of T2D remain to be characterized. Liquid chromatography coupled to tandem mass spectromet...

2017-04-26 | MTBLS352 | MetaboLights
TranscriptomicsTranscriptome sequencing of naked mole rat, Heterocephalus glaber
Deep sequencing of mRNA from naked mole rat Analysis of ploy(A)+ RNA of different specimens: brain, kidney, liver from new born , 4 years old , 20 years old and 4 years old hypoxia-exposed naked mole rat
ORGANISM(S): Heterocephalus glaber 
2011-10-12 | E-GEOD-30337 | biostudies-arrayexpress
Proteomics4D label-free proteomics data of yellowfin tuna
4D proteomic analysis of yellowfin tuna dorsal meat from ultrasound-assisted salting and salted frozen storage for 7 days
ORGANISM(S): Thunnus Albacares 
2024-01-02 | PXD048206 |
ProteomicsHs_C-HPP_EnrichmentStrategy_membrane
Enrichment strategy for searching missing protein, HCCLM6 and MHCC97L, membrane and
ORGANISM(S): Homo Sapiens (human) 
2015-12-31 | PAe005437 | PeptideAtlas
ProteomicsHs_C-HPP_EnrichmentStrategy_LMW_Gel_Serum
Enrichment strategy for searching missing protein, LMW Proteins, in-house Gel-filter system
ORGANISM(S): Homo Sapiens (human) 
2015-12-31 | PAe005367 | PeptideAtlas
ProteomicsHs_C-HPP_EnrichmentStrategy_Phospho_HCCLM6
Enrichment strategy for searching missing protein, HCCLM6, Phospho
ORGANISM(S): Homo Sapiens (human) 
2015-12-31 | PAe005398 | PeptideAtlas
ProteomicsHs_C-HPP_EnrichmentStrategy_HCCLM6-Nuclear
Enrichment strategy for searching missing protein, HCCLM6, nuclear
ORGANISM(S): Homo Sapiens (human) 
2015-12-31 | PAe005357 | PeptideAtlas
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