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ProteomicsProteomics insights into the molecular mechanisms of c9, t11-CLA synthesis
Cis-9, trans-11-conjugated linoleic acid (c9, t11-CLA), a functional fatty acid, is one of the research hotspots in the fields of functional dairy products development because of its multiple beneficial effects in humans and animals. In milk, most c9, t11-CLA is de novo synthesized from trans-11-oct...
ORGANISM(S): Bos taurus (Bovine) 
2022-08-12 | PXD028620 | Pride
Cis-9 Trans-11-conjugated linoleic acid  stearoyl-coa desaturase 1  mac-t cells  proteomics  functional fatty acid 
MetabolomicsMethionine Intervention Induces PD-L1 Expression to Enhance the Immune Checkpoint Therapy Response in MTAP-deleted Osteosarcoma
Osteosarcoma (OS), a malignant bone tumor with limited treatment options, exhibits low sensitivity to immune checkpoint therapy (ICT). Through genomics and transcriptomics analyses, we have identified a subgroup of OS with methylthioadenosine phosphorylase (MTAP) deletion, which contributes to ICT r...
2026-06-09 | MTBLS11985 | MetaboLights
TranscriptomicsExpression data from SW480 cells with Gankyrin knockdown
We performed genome-wide screening using SW480 cells with Gankyrin knockdown on an Affymetrix gene expression array to identify the transcriptional targets of Gankyrin. Transcriptional profiling with samples from SW480 cells that were infected with control or gankyrin shRNA. Two condition experiment...
ORGANISM(S): Homo sapiens 
2013-02-04 | E-GEOD-44029 | biostudies-arrayexpress
UnknownAssociation of inflammatory susceptibility genes with myopia in Chinese children.
Not available
S-EPMC12553560 | biostudies-literature
UnknownCCR7 expression and intratumoral FOXP3+ regulatory T cells are correlated with overall survival and lymph node metastasis in gastric cancer.
Not available
S-EPMC3764061 | biostudies-literature
UnknownEffects of a Trans-Theoretical Model-Based Health Education Program on the Management of Cognitive Dysfunction in Older Adults With Mild Cognitive Impairment: Study Rationale and Protocol Design for a Randomized Controlled Trial.
Not available
S-EPMC7838522 | biostudies-literature
UnknownNanosensitizer-mediated augmentation of sonodynamic therapy efficacy and antitumor immunity.
Not available
S-EPMC10620173 | biostudies-literature
UnknownNodulation Characterization and Proteomic Profiling of Bradyrhizobium liaoningense CCBAU05525 in Response to Water-Soluble Humic Materials.
Not available
S-EPMC4650689 | biostudies-literature
ProteomicsUBA2-High Osteosarcoma Suppresses Immune Infiltration by Autophagy-Mediated MHC-I Degradation
Osteosarcoma (OS) responds poorly to immune-checkpoint blockade (ICB), and the molecular drivers of its immune-cold state remain unclear. Using multi-omics analyses, we identified an immune-cold OS subtype characterized by enrichment of protein SUMOylation and found the SUMO E1 subunit UBA2 as a key...
ORGANISM(S): Homo Sapiens 
2026-01-28 | PXD073700 |
UnknownLysophosphatidylcholine trigger myocardial injury in diabetic cardiomyopathy via the TLR4/ZNF480/AP-1/NF-kB pathway.
Not available
S-EPMC11260982 | biostudies-literature
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