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A rexinoid, targretin (TRG) and two retinoids, 9-cis retinoic acid (9cRA) and 4-hydroxyphenylretinamide (4HPR) were examined for their effects on gene expression in rat mammary gland, liver, and lung tissues. The chemopreventive effects of these agents have largely been attributed to their ability t...
ORGANISM(S): Rattus norvegicus 
Differentiation of SH-SY5Y cells by 9 cis retinoic acid
Primary inflammatory pathologies caused by phagocytes lead to numerous debilitating conditions, ranging from chronic pain to permanent blindness. Siglec-9 is an immunoinhibitory receptor expressed on many types of phagocytes and is a promising target for anti-inflammatory therapeutics. We developed ...
ORGANISM(S): Homo sapiens (Human) 
2021-01-14 | PXD018774 | Pride
The effect of CLA on gene expression in Caco-2 cells Experiment Overall Design: Caco-2 cells were treated with linoleic acid (LA; the parent and control fatty acid) trans-10, cis-12 CLA or cis-9, trans-11 CLA for 12 d.
ORGANISM(S): Homo sapiens 
9-cis-retinoic acid improves disease modelling in iPSC-derived liver organoids
Trans-10, Cis-12 conjugated linoleic acid (t10c12 CLA) causes fat loss in mouse 3T3-L1 adipocyte tissue culture; however cis-9, trans-11 CLA does not (this series). The early transcriptome changes were analyzed using high-density microarrays to better characterize the signaling pathways responding t...
ORGANISM(S): Mus musculus 
The RNA seq analysis aims to determine the changes in gene expression between undifferentiated and differentiated SH SY5Y neuroblastoma cells following differentiation with 9 cis retinoic acid.
ORGANISM(S): Homo sapiens 
2024-09-24 | GSE151554 | GEO
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