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TranscriptomicsProstatic Stromal Cell Gene Expression
We generated prostatic stromal microarray expression data for functional validation of our LOH/AI hot-/cold-spots in stroma. Stromal cells from normal peripheral zone tissue and from tumors are grown in culture, and were analyed on gene expression platform. Stromal cells cultured from normal periphe...
ORGANISM(S): Homo sapiens 
2012-02-27 | E-GEOD-34312 | biostudies-arrayexpress
ProteomicsTHEM6-mediated lipid remodelling sustains stress resistance in cancer (Part3 : THEM6 KO in LNCaP AI)
Despite the clinical benefit of androgen-deprivation therapy (ADT), the majority of patients with advanced prostate cancer (PCa) ultimately develop lethal castration-resistant prostate cancer (CRPC). In this study, we identified thioesterase superfamily member 6 (THEM6) as a marker of ADT resistance...
ORGANISM(S): Homo sapiens (Human) 
2021-12-11 | PXD024433 | Pride
Castration-resistant prostate cancer Cancer metabolism Endoplasmic reticulum Cancer proteomics 
UnknownA benchmark of expert-level academic questions to assess AI capabilities.
Not available
S-EPMC12851929 | biostudies-literature
UnknownComplete genome sequence of Bacillus thuringiensis strain HD521.
Not available
S-EPMC4572618 | biostudies-literature
ProteomicsIntegrated phosphoproteomic profiling and causal analysis reveal signaling relations in GPVI/ITAM-mediated platelet activation programs
Platelets engage cues of pending endothelial dysfunction through coordinated adhesion, secretion and aggregation responses. These rapid changes in platelet phenotype are orchestrated by intracellular mechanisms that remain systematically undefined. This study develops a TMT-SPS-MS3 phosphoproteomics...
ORGANISM(S): Homo sapiens (Human) 
2020-11-20 | PXD017167 | Pride
Human Platelets Causal pathways Cardiovascular disease Isobaric labeling Activation Phosphopeptide enrichment Quantitative proteomics Signaling 
UnknownA foundation model for generalizable disease detection from retinal images.
Not available
S-EPMC10550819 | biostudies-literature
UnknownMachine learning derived retinal pigment score from ophthalmic imaging shows ethnicity is not biology.
Not available
S-EPMC11696055 | biostudies-literature
UnknownThrombin induces ACSL4-dependent ferroptosis during cerebral ischemia/reperfusion.
Not available
S-EPMC8866433 | biostudies-literature
UnknownMechanical ventilation in patients with cardiogenic pulmonary edema: a sub-analysis of the LUNG SAFE study.
Not available
S-EPMC9791731 | biostudies-literature
UnknownSpontaneous Breathing in Early Acute Respiratory Distress Syndrome: Insights From the Large Observational Study to UNderstand the Global Impact of Severe Acute Respiratory FailurE Study.
Not available
S-EPMC6336491 | biostudies-literature
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