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UnknownAccurate de novo design of heterochiral protein-protein interactions.
Not available
S-EPMC11614891 | biostudies-literature
MetabolomicsLimited survival and impaired hepatic fasting metabolism of glucose, amino acids and lipids in mice with constitutive Rag GTPase signaling
The mechanistic target of rapamycin complex 1 (mTORC1) integrates cellular nutrient signaling and hormonal cues to control metabolism. We have previously shown that constitutive nutrient signaling to mTORC1 by means of genetic activation of RagA (RagAGTP) in mice resulted in a fatal energetic crisis...
2021-05-11 | MTBLS2397 | MetaboLights
MetabolomicsComparative metabolomic analysis of exudates of microcystin-producing and microcystin-free Microcystis aeruginosa strains

Cyanobacterial harmful algal blooms (cHABs) dominated by Microcystis aeruginosa threaten the ecological integrity and beneficial uses of lakes globally. In addition to producing hepatotoxic microcystins (MC), M. aeruginosa exudates (MaE) contain various compounds with demonstrat...

2023-01-16 | MTBLS6603 | MetaboLights
TranscriptomicsTranscription profiling of Arabidopsis LEC1-overexpressing transgenic plants reveals LEAFY COTYLEDON1 is a key regulator of fatty acid biosynthesis in Arabidopsis thaliana
In plants, fatty acids are de novo synthesized predominantly in plastids fromacetyl-CoA. Although fatty acid biosynthesis has been biochemically well-studied, little isknown about the regulatory mechanisms of the pathway. Here, we show that overexpressionof the Arabidopsis (Arabidopsis thaliana) LEA...
ORGANISM(S): Arabidopsis thaliana 
2008-10-25 | E-GEOD-12137 | biostudies-arrayexpress
TranscriptomicsTranscriptome sequencing on a time series of potato infected with Globodera pallida to explore the sex determination
We explored the sex determination of Globodera pallida. To do so, we grew cuttings of the potato cultivar Desiree on Gamborg B5 medium supplemented with either 1.5 g/L or 20 g/L sucrose. 14-day-old cuttings were inoculated with 100 G. pallida E400 Rookmaker juveniles. Infected root tissue was harves...
ORGANISM(S): Globodera pallida 
2025-11-25 | E-MTAB-16117 | biostudies-arrayexpress
UnknownIdentification of a de novo variant in the ASXL2 gene related to Shashi-Pena syndrome.
Not available
S-EPMC10655504 | biostudies-literature
ProteomicsInvestigating the Quantitative Proteomics of TMT Phosphorylation in Ningxia Wolfberry under Diverse Concentrations of Salt Stress: Unveiling Molecular Mechanisms and Implications
The experimental results revealed 2727 phosphorylated proteins, 5258 phosphorylated peptides and 5096 phosphorylation sites, which included 5252 quantifiable phosphorylated peptides and 5091 quantifiable phosphorylation sites on 2725 quantifiable modified proteins
ORGANISM(S): Lycium Barbarum 
2024-12-10 | PXD058720 |
UnknownRNA-Seq analysis of Clerodendrum inerme (L.) roots in response to salt stress.
Not available
S-EPMC6785863 | biostudies-literature
TranscriptomicsRegulation of pluripotency and self-renewal of ES cells through epigenetic-threshold modulation and mRNA pruning
The core pluripotency factors (Oct4, Sox2, and Nanog), the Myc network, and the chromatin-modifying complexes such as PRC2 ensure the pluripotency and self-renewal of ES cells (ESC). How these factors coordinate with one another remains poorly understood. We report that Utf1, a target of Oct4 and So...
ORGANISM(S): Mus musculus 
2012-10-26 | E-GEOD-39513 | biostudies-arrayexpress
UnknownGenome-Wide Analysis of the <i>LEA</i> Gene Family in Pineapple (<i>Ananas comosus</i> L.) Reveals Its Potential Roles in Cold Stress Response and Reproductive Development.
Not available
S-EPMC12729617 | biostudies-literature
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