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TranscriptomicsMutation Mapping of 31 Streptococcus suis strains
Identification of Genes and Genomic Islands Correlated with High Pathogenicity through Tilling Microarray-Based Comparative Genomics in S. suis. Streptococcus suis is an important zoonotic pathogen that can cause meningitis and sepsis in both pigs and humans. S. suis isolates have been categorized ...
ORGANISM(S): Streptococcus suis 
2012-08-08 | E-GEOD-26052 | biostudies-arrayexpress
UnknownLabel-Free Quantitative Proteomic Analysis of Differentially Expressed Membrane Proteins of Pulmonary Alveolar Macrophages Infected with Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus and Its Attenuated Strain.
Not available
S-EPMC6084361 | biostudies-literature
MetabolomicsBile acid is a significant host factor shaping the gut microbiome of diet induced obese mice (targeted short chain fatty acid analysis assay)

BACKGROUND: Intestinal bacteria are known to regulate the bile acid (BA) homeostasis via intestinal biotransformation of BAs and stimulating the expression of fibroblast growth factor 19 through intestinal nuclear farnesoid X receptor (FXR). On the other hand, BAs directly regula...

2017-11-23 | MTBLS546 | MetaboLights
UnknownHelicobacter pylori-induced YAP1 nuclear translocation promotes gastric carcinogenesis by enhancing IL-1β expression.
Not available
S-EPMC6639191 | biostudies-literature
UnknownThe effect of haptoglobin genotype on the association of asymmetric dimethylarginine and DDAH 1 polymorphism with diabetic macroangiopathy.
Not available
S-EPMC9716717 | biostudies-literature
UnknownIdentification of factors affecting fattening efficiency of commercial pig herds and analysis of their impact at different performance levels.
Not available
S-EPMC11362584 | biostudies-literature
MetabolomicsPaeonol Ameliorates Ulcerative Colitis in Mice by Modulating the Gut Microbiota and its Metabolites

BACKGROUND: Ulcerative colitis (UC) is a chronic recurrent inflammatory disease of the gastrointestinal tract. Recent studies demonstrate that the phenolic tannin paeonol (Pae) attenuates UC in mouse models by downregulating inflammatory factors; however, molecular mechanisms lin...

2024-09-27 | MTBLS5204 | MetaboLights
TranscriptomicsKnockout PTTG1 HCT116 cells
To identify potential PTTG1-targeted genes, total RNA from PTTG1+/+ and PTTG1-/- HCT 116 cells was isolated using the RNeasy Kit (Qiagen) and analyzed using Illumina microarrays (HumanHT-12_V4). Raw data were processed according to the manufacturerâ??s standard procedure and further analyzed using ...
ORGANISM(S): Homo sapiens 
2015-11-23 | E-GEOD-58863 | biostudies-arrayexpress
GenomicsA histone H3.3 Lysine 36 Trimethylation Reader Connects Chromatin to Regulated Pre-mRNA Processing
BS69 (aka ZMYND11) was initially discovered as a direct target of adenoviral E1A oncoprotein1. Subsequent studies implicated BS69 as a tumor suppressor and a transcriptional regulator2. But exactly how BS69 regulates gene expression has remained elusive. BS69 contains tandemly arranged PHD, BROMO an...
ORGANISM(S): Homo sapiens 
2014-09-03 | E-GEOD-51672 | biostudies-arrayexpress
MetabolomicsNon-targeted multimodal metabolomics and lipidomics data from ovine rumen fluid fractions

From an animal production and health perspective, our understanding of the metabolites in ruminant biofluids, particularly rumen fluid across different host species is poorly understood. Metabolomics is a powerful and sensitive approach for investigating low molecular weight metabolite profiles p...

2021-08-23 | MTBLS1717 | MetaboLights
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