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Elaiophylin was screened and identified as a novel autophagy inhibitor, with significant antitumor efficacy as a single agent. To explore the mechanisms by which elaiophylin kills cancer cells, NimbleGen 12x135K microarrays were used to find the gene expression changes in SKOV3 cells treated with el...
ORGANISM(S): Homo sapiens 
2022-06-07 | GSE205529 | GEO
RNA sensing is critical for RLR activation and downstream signaling. To identify molecules that are involved in modulating viral RNA recognition, we utilized biotin-labeled 60 nt single-stranded RNA (ssRNA) from SARS-CoV-2 NSP1 coding region (NSP1 ssRNA) to pull down proteins from RAW264.7 cells. Th...
ORGANISM(S): Mus musculus (Mouse) 
2026-04-08 | PXD064808 | Pride
Extracellular perception of auxin, an essential phytohormone in plants, has been debated for decades. Auxin binding protein 1 (ABP1) physically interacts with quintessential transmembrane kinases (TMKs) and was proposed to act as an extracellular auxin receptor, but its role was disputed because abp...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2023-11-25 | PXD044623 | Pride
Benzene is known to be a common toxic industrial chemical, and prolonged benzene exposure may cause nervous system damage. At present, there were few studies on benzene-induced neurological damage. This research aimed to identify protein biomarkers to predict central nervous system damage of benzene...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-06 | PXD046028 | Pride
Alterations in the gene expression profile in SKOV3 cells exposed to elaiophylin
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