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TranscriptomicsmiRNA profiles in livers with different mass deficits after partial hepatectomy and miR-106b~25 cluster accelerating hepatocyte proliferation in rats
To query the relationship between miRNA profiles and deficits in liver mass after PH and the miRNAs linked to liver regeneration, we compared the miRNA expression profile after 2/3 PH, a standard procedure that leads to robust DNA synthesis, with that after 1/3 PH, a procedure that causes minimal re...
ORGANISM(S): Rattus norvegicus 
2016-04-06 | E-GEOD-79983 | biostudies-arrayexpress
UnknownThe inhibition of FKBP5 protects β-cell survival under inflammation stress via AKT/FOXO1 signaling.
Not available
S-EPMC10349081 | biostudies-literature
TranscriptomicsHsp27 acts as a master molecular chaperones and plays an essential role in hepatocellular carcinoma metastasis
Hsp27 can regulate multiply signaling pathway and protect HCC cells apoptosis by mediating interaction with its cochaperones 3 HepG2 samples stably transfected with Hsp27 ORF vectors, Hsp27 shRNA or control vectors
ORGANISM(S): Homo sapiens 
2012-05-21 | E-GEOD-38080 | biostudies-arrayexpress
ProteomicsThe p-MYH9/USP22/HIF-1α axis promotes lenvatinib resistance and cancer stemness in hepatocellular carcinoma
To understand the role of HIF1a in lenvatinib resistance, we conducted label-free quantitative proteome analysis in both control and lenvatinib resistance cell lines. This analysis revealed changes in the proteome due to the lenvatinib resistance, providing a valuable reference for further investiga...
ORGANISM(S): Homo Sapiens 
PXD055440 |
ProteomicsMulti-omic analysis reveals a CAF-stemness-governed classification in HCC liver transplant recipients
In patients with hepatocellular carcinoma (HCC) meeting the Milan criteria, liver transplantation (LT) is an effective therapy. This study aims to define the survival-related molecular biological features helping precisely identifying the patients with HCC beyond the Milan criteria who have acceptab...
ORGANISM(S): Homo Sapiens 
2025-02-24 | PXD061119 |
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