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TranscriptomicsSplicing function of mitotic regulators links R-loop mediated DNA damage to tumor cell killing
We discovered that two mitotic regulators, BuGZ and Bub3, involved in splicing regulation during interphase 8 samples from primary Human foreskin fibroblast cells (HFFs) , 12 samples from TOV21G cells. Control siRNA. BuGZ siRNA or Bub3 siRNA were transfected for 48 h before sample collection. Cells ...
ORGANISM(S): Homo sapiens 
2015-04-11 | E-GEOD-67770 | biostudies-arrayexpress
UnknownA Comprehensive Study Employing Computational Analysis and Mendelian Randomization Has Revealed the Impact of Key Genes on Liver Cancer.
Not available
S-EPMC12190003 | biostudies-literature
TranscriptomicsRegulation of pluripotency and self-renewal of ES cells through epigenetic-threshold modulation and mRNA pruning
The core pluripotency factors (Oct4, Sox2, and Nanog), the Myc network, and the chromatin-modifying complexes such as PRC2 ensure the pluripotency and self-renewal of ES cells (ESC). How these factors coordinate with one another remains poorly understood. We report that Utf1, a target of Oct4 and So...
ORGANISM(S): Mus musculus 
2012-10-26 | E-GEOD-39513 | biostudies-arrayexpress
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