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ProteomicsKidney transcriptomic and proteomic analyses provide new insight into the pathogenesis of IgA nephropathy in mice
Background:Immunoglobulin A nephropathy (IgAN) is a common clinically refractory disease, and its pathogenesis remains unclear. Studying the pathogenesis of IgA nephropathy is of great significance for the clinical treatment of IgA nephropathy. Methods:The IgAN mouse model was established through or...
ORGANISM(S): Mus Musculus 
2024-08-15 | PXD054916 |
ProteomicsHuman Epididymis Protein 4 Promotes Aberrant Epithelial-Fibroblast Crosstalk in Pulmonary Fibrosis
Invasive lung myofibroblasts are the main cause of tissue remodeling in idiopathic pulmonary fibrosis (IPF). A key mechanism contributing to this important feature is aberrant crosstalk between the abnormal/injured lung epithelium and pulmonary fibroblasts. Here, we demonstrated that lungs from pati...
ORGANISM(S): Homo Sapiens 
2024-12-17 | PXD058959 |
ProteomicsProteomics and Organoid Culture Reveal the Underlying Pathogenesis of Hashimoto's Thyroiditis
To understand Hashimoto's Thyroiditis and translate this knowledge to clinical applications, we took mass spectrometric analysis on thyroid tissue fine-needle puncture from HT patients and healthy people in an attempt to make a further understanding of the pathogenesis of Hashimoto's Thyroiditis.
ORGANISM(S): Homo Sapiens 
2021-09-10 | PXD028448 |
ProteomicsNociceptive neurons inhibit neutrophil extracellular trap formation via MLKL-licensed histone release
This data set contains the raw data of proteinomic analysis of dorsal root ganglions (DRGs) in WT and MLKL-KO mice under basal condition and after CFA treatment, and MLKL-based IP-MS analysis of WT DRGs under basal condition and after CFA treatment.
ORGANISM(S): Mus Musculus 
2026-04-16 | PXD077273 |
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