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TranscriptomicsEvaluation of effect of PTEN gene deletion in mouse CD4+ Th1 clones after stimulation
PTEN is thought to play a critical role in T cell activation by negatively regulating the PI3K signaling pathway important for cellular activation, growth, and proliferation. T cells from mice in which PTEN was conditionally deleted in the thymus were reported to display CD28-independent IL-2 produ...
ORGANISM(S): Mus musculus 
2013-02-01 | E-GEOD-43936 | biostudies-arrayexpress
UnknownHelicobacter pylori SlyD stabilizes TPT1 via hnRNPK and enhances OCT1-mediated CDX2 transcriptional activation to drive gastric intestinal metaplasia.
Not available
S-EPMC11803974 | biostudies-literature
Genomicsena-DATASET-BIOPIC-06-06-2018-15:24:14:117-163 - samples
bulk RNA-seq data of the 5 HCC patinets. Single cell RNA seq data of these patients was under the accession number EGAD00001003337
EGAD00001004148 | EGA
Genomicsena-DATASET-BIOPIC-06-06-2018-15:55:49:835-165 - samples
bulk Exome-seq data of the 5 HCC patinets. Single cell RNA seq data of these patients was under the accession number EGAD00001003337
EGAD00001004149 | EGA
Genomicsena-DATASET-BIOPIC-16-05-2017-14:34:15:534-498 - samples
T cells isolated from peripheral blood, tumors and adjacent normal tissues from six hepatocellular carcinoma patients. SmartSeq2 and Tang2009 protocol were used to amplify RNA from single T cells. High depth enables simultaneously expression profiling and TCR assembling.
EGAD00001003337 | EGA
GenomicsSingle-cell RNA sequencing on 5063 single T cells isolated from peripheral blood, tumour and adjacent normal tissues from six hepatocellular carcinoma patients.
Single-cell RNA sequencing on 5063 single T cells isolated from peripheral blood, tumour and adjacent normal tissues from six hepatocellular carcinoma patients. The transcriptional properties of these individual cells, coupled with the assembled T cell receptor (TCR) sequences, were used to delineat...
EGAS00001002072 | EGA
GenomicsPeking University BIOPIC Data Access Committee (PUBDAC).The DATA ACCESS AGREEMENT is provided at https://github.com/zhangyybio/single-T-cell-data-access. Applicants can request access to the data by directly downloading it or by sending an email to cancerpku@pku.edu.cn. The process that is used to approve an application includes verifying the institution, participants and research purposes of the application. In general this process will take about two weeks. In principal, any academic research
Data Access Committee EGAC00001000551
EGAC00001000551 | EGA
ProteomicsA Stress-Adaptive Lipid Kinase Axis Defines Metabolic Vulnerabilities in Neuroendocrine Prostate Cancer
Neuroendocrine prostate cancer (NEPC) persists in a profoundly hypoxic microenvironment, yet the mechanisms enabling tumor adaptation to this metabolically challenging niche remain undefined. Here, we identify the lipid kinase PIKfyve as overexpressed in NEPC, functioning as a central node in a stre...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD076640 | Pride
UnknownExpression Pattern of FT/TFL1 and miR156-Targeted SPL Genes Associated with Developmental Stages in Dendrobium catenatum.
Not available
S-EPMC6600168 | biostudies-literature
UnknownDiscovery of the first selective and potent PROTAC degrader for the pseudokinase TRIB2.
Not available
S-EPMC12135709 | biostudies-literature
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