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UnknownShen-Zhi-Ling oral liquid ameliorates cerebral glucose metabolism disorder in early AD via insulin signal transduction pathway in vivo and in vitro.
Not available
S-EPMC8638512 | biostudies-literature
ProteomicsProtein profile analysis of 12 human vitreous samples using labelfree method
To study the differences in protein profiles before and after intravitreal ranibizumab (IVR) treatment, 12 vitreous humor (VH) samples were collected from 6 proliferative diabetic retinopathy (PDR) patients before (pre group) and after IVR treatment (post group). LC–MS/MS and bioinformatics analysis...
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD027592 | Pride
Proliferative diabetic retinopathy  proteomics  ranibizumab  label-free  lc–ms/ms  prm 
ProteomicsChange of Ranibizumab-induced Human Vitreous Protein Profile in Patients with Proliferative Diabetic Retinopathy Based on Proteomics Analysis
Background: Preoperative treatment of anti-vascular endothelial growth factor (VEGF) agents is extensively used in proliferative diabetic retinopathy (PDR), but the molecular mechanism is not fully understood. The objective of this research is to observe change of protein profile induced by Ranibizu...
ORGANISM(S): Homo sapiens (Human) 
2018-10-19 | PXD008901 | Pride
Proteomics  proliferative diabetic retinopathy  ranibizumab 
UnknownFast end-to-end surface interpretation of SARS-CoV-2 variants by differentiable molecular surface interaction fingerprinting method.
Not available
S-EPMC10570951 | biostudies-literature
UnknownTumor microenvironment and immunotherapy for triple-negative breast cancer.
Not available
S-EPMC11689763 | biostudies-literature
ProteomicsClpP participates in stress response, biofilm formation, antimicrobials tolerance, and virulence of Enterococcus faecalis and its global substrate proteins were identified by mass spectrometer with Tandem Mass Tags (TMT) labeling
ClpP is important for bacterial growth and plays an indispensable role in cellular protein quality control systems by refolding or degrading damaged proteins, but the role of ClpP on Enterococcus faecalis is still obscure. A clpP deletion mutant (△clpP) was constructed in E. faecalis strain OG1RF in...
ORGANISM(S): Enterococcus faecalis (Streptococcus faecalis) 
2020-03-06 | PXD014211 | Pride
Enterococcus faecalis  clpp  stress tolerance  biofilm formation  virulence 
UnknownGPI-anchored ligand-BioID2-tagging system identifies Galectin-1 mediating Zika virus entry.
Not available
S-EPMC9668739 | biostudies-literature
TranscriptomicsTranscriptome analysis of ROP10 GTPase-mediated abscisic acid (ABA) signaling in Arabidopsis
In this study, we have identified genes that are respectively activated and repressed by the low concentration of ABA and show that ROP10 gates a specific subset of genes that are responsive only to a low ABA concentration. Keywords: Whole seedlings of wild-type (Ws) and the mutant (rop10-1) treated...
ORGANISM(S): Arabidopsis thaliana 
2005-11-14 | E-GEOD-3454 | biostudies-arrayexpress
ProteomicsMolecular characterization of advanced colorectal cancer using serum proteomics and metabolomics
To comprehensively reveal molecular characterization of advanced CRC, we applied integrated proteomic and metabolomic analyses on serum samples from 20 patients with CRC at stage III or IV. Methods In the present study, we took advantage of nanoscale liquid chromatography and quadrupole time-of-flig...
ORGANISM(S): Homo Sapiens 
2021-03-29 | PXD025041 |
MetabolomicsGut microbiota-driven regulation of queen bee ovarian metabolism

With the global prevalence of Varroa mites, more and more beekeepers resort to confining the queen bee in a queen cage to control mite infestation or to breed superior and robust queen bees. However, the impact of such practices on the queen bee remains largely unknown. Therefore, we sub...

2023-09-11 | MTBLS7576 | MetaboLights
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