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ProteomicsPhosphoproteomics reveals regulation of secondary metabolites in Mahonia bealei under ultraviolet-B radiation
Mahonia Bealei was used as a traditional Chinese medicine for its high alkaloid content. Previous research found that alkaloid and flavonoid contents in the M. bealei leaves increased under combinatory treatments of ultraviolet B and dark. In order to explore the underlying response mechanism, TiO2 ...
ORGANISM(S): Mahonia 
2022-02-16 | PXD028873 | Pride
Phosphoproteomics  mahonia bealei  ultraviolet-b radiation  abiotic stress  secondary metabolism 
MetabolomicsDifferent regions of synaptic vesicle membrane regulate VAMP2 conformation for the SNARE assembly
Vesicle associated membrane protein 2 (VAMP2/synaptobrevin2), a core SNARE protein residing on synaptic vesicles (SVs), forms helix bundles with syntaxin-1 and SNAP25 for the SNARE assembly. Prior to the SNARE assembly, the structure of VAMP2 is unclear. Here, by using in-cell NMR spectroscopy, we d...
2021-10-06 | MTBLS1503 | MetaboLights
UnknownCpG methylation patterns of human mitochondrial DNA.
Not available
S-EPMC4800444 | biostudies-literature
UnknownTargeted knockdown of Notch1 inhibits invasion of human prostate cancer cells concomitant with inhibition of matrix metalloproteinase-9 and urokinase plasminogen activator.
Not available
S-EPMC2951134 | biostudies-literature
TranscriptomicsLamin binding profiles in the ENCODE regions
A systems understanding of nuclear organization and events is critical for determining how cells divide, differentiate and respond to stimuli and for identifying the causes of diseases. Chromatin remodeling complexes such as SWI/SNF have been implicated in a wide variety of cellular processes includ...
ORGANISM(S): Homo sapiens 
2011-01-10 | E-GEOD-24382 | biostudies-arrayexpress
UnknownGenomic basis of schistosome resistance in a molluscan vector of human schistosomiasis.
Not available
S-EPMC11699755 | biostudies-literature
TranscriptomicsmRNA regulation in normal or TNF-a/IL-4-activated bronchial epithelial cells (BEAS-2B)
Illumina microarray experiment on BEAS-2B cells. Cells were seeded 24 h before TNF-a/IL-4 (50 ng/ml) treatment that lasted for 18 h. Cytoplasmic RNA of both normal and activated BEAS-2B cells were collected for microarray. Cells were seeded 24 h before TNF-a/IL-4 (50 ng/ml) treatment that lasted f...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-13119 | biostudies-arrayexpress
ProteomicsLC-MS/MS analysis of B12 treated SH-SY5Y cells
B12 is a compound that has neuroprotective effects. We investigated the protein expression profile associated with the neuroprotective effects of B12 on human neuronal cells SH-SY5Y using label-free quantitative proteomics.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2015-12-29 | MSV000079437 | MassIVE
ProteomicsProteomic analysis revealed gender-related differences in the skin mucus proteome of discus fish (Symphysodon haraldi) during the parental and non-parental care periods
The discus fish, Symphysodon spp., a South American cichlid, has a unique parental care behavior where fry bite on parental skin mucus after hatching. In this study, we used LC-MS/MS technique to compare the skin mucus proteome composition of male or female discus fish during parental and non-parent...
ORGANISM(S): Symphysodon Haraldi 
PXD054942 |
ProteomicsIDH1-mutant metabolite D-2-Hydroxyglutarate inhibits proliferation and sensitizes glioma to Temozolomide via down-regulating ITGB4/PI3K/AKT
The effects of D-2HG on U251 cells by conducting a proteomic analysis
ORGANISM(S): Homo Sapiens 
PXD052264 |
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