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GenomicsTranscription factor Achaete-Scute homologue 2 initiates T follicular helper cell development [ChIP-Seq]
In immune responses, activated T cells migrate to B cell follicles and develop to T follicular helper (Tfh) cells, a new subset of CD4+ T cells specialized in providing help to B lymphocytes in the induction of germinal centers 1-3. Although Bcl6 has been shown to be essential in Tfh cell function, ...
ORGANISM(S): Mus musculus 
2014-01-01 | E-GEOD-52839 | biostudies-arrayexpress
ProteomicsTargeting Pim2 Improves Effector Function and Longevity of CD8 T cells in Cancer Immunotherapy
The Pim kinase family is critically involved in tumorigenesis, yet its function in primary T cells remains poorly understood. We previously reported that Pim2 negatively regulates T-cell responses to alloantigen. To investigate how Pim2 impacts anti-tumor immunity of CD8 T cells, we generated Pim2-/...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-08 | PXD059837 | Pride
Pim2 T cells Cancer Immunotherapy 
UnknownAn External CAM Therapy (Tian Jiu) versus Placebo in Treatment of Allergic Rhinitis: A Pilot Single-Blinded, Three-Arm, Randomized Controlled Study.
Not available
S-EPMC6487095 | biostudies-literature
ProteomicsComparative analysis of maca (Lepidium meyenii) proteome profiles reveals insights into response mechanisms of herbal plants to high-temperature stress
High-temperature stress (HTS) is one of the main environmental stresses that limit plant growth and crop production in agricultural systems. Maca (Lepidium meyenii) is an important high-altitude herbaceous plant adapted to a wide range of environmental stimuli such as cold, strong wind and UV-B expo...
ORGANISM(S): Lepidium meyenii 
2020-08-25 | PXD021042 | Pride
High-temperature stress Stress response Tandem mass tag Molecular mechanism Maca 
UnknownMesenchymal stem cell-based tissue regeneration is governed by recipient T lymphocytes via IFN-γ and TNF-α.
Not available
S-EPMC3233650 | biostudies-literature
UnknownEpidermal injury and infection during poxvirus immunization is crucial for the generation of highly protective T cell-mediated immunity.
Not available
S-EPMC3070948 | biostudies-literature
UnknownCell membrane patches transfer CAR molecules from a cellular depot to conventional T cells for constructing innovative fused-CAR-T cells without necessitating genetic modification.
Not available
S-EPMC11302086 | biostudies-literature
MetabolomicsCell Membrane Remodeling Mediates Polymyxin B Resistance in Klebsiella pneumoniae: An Integrated Proteomics and Metabolomics Study
Polymyxin B (PB) is introduced into the clinic as the last-line therapy against carbapenem-resistant Klebsiella pneumoniae (CRKP). Unfortunately, increased resistance to PB in Klebsiella pneumoniae (K. pneumoniae) has threatened global health. Resistance of K. pneumoniae ...
2022-03-04 | MTBLS4132 | MetaboLights
UnknownIdentification and characterization of the Cucurbitacins, a novel class of small-molecule inhibitors of Tropomyosin receptor kinase a.
Not available
S-EPMC6836411 | biostudies-literature
UnknownCharacterization of Pathogenic CD8+ T cells in Chlamydia-Infected OT1 Mice.
Not available
S-EPMC8788780 | biostudies-literature
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