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ProteomicsHistone chaperone ASF1 mediates H3.3-H4 deposition in Arabidopsis
Histone chaperones and chromatin remodelers control nucleosome dynamics, essential for transcription, replication, and DNA repair. The histone chaperone Anti-Silencing Factor 1 (ASF1) plays a central role in facilitating CAF-1-mediated replication-dependent H3.1 deposition and HIRA-mediated replicat...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2022-10-31 | PXD035578 | Pride
Arabidopsis Lcms Proteomics 
ProteomicsNAP1-RELATED PROTEIN1 and 2 negatively regulate H2A.Z abundance in chromatin in Arabidopsis
In eukaryotes, DNA wraps around histones to form nucleosomes, which are compacted into chromatin. DNA-templated processes, including transcription, require chromatin disassembly and reassembly mediated by histone chaperones. Additionally, distinct histone variants can replace core histones to regula...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2020-05-18 | PXD019248 | Pride
Arabidopsis Lc-ms/ms 
ProteomicsArabidopsis MORC proteins function in the efficient establishment of RNA directed DNA methylation
The Microrchidia (MORC) family of ATPases are required for transposable element (TE) silencing and heterochromatin condensation in plants and animals, and C. elegans MORC-1 has been shown to topologically entrap and condense DNA. In Arabidopsis thaliana, mutation of MORCs has been shown to reactivat...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2021-07-02 | PXD026674 | Pride
Arabidopsis morc7 
ProteomicsComputational and Experimental Verification of Cabozantinib to Inhibit DNA Damage Repair in Liver Cancer
The proteomics study of cabozantinib-treated hepatocellular carcinoma cells.
ORGANISM(S): Homo Sapiens 
2025-11-13 | PXD070703 |
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