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TranscriptomicsDiscovery of the genes controlled by the second messenger cyclic di-GMP in Mycobacterium tuberculosis
Cyclic di-GMP (c-di-GMP) is a ubiquitous second messenger that regulates many biological processes in bacteria. The genome in Mycobacterium tuberculosis encodes a single copy of the diguanylate cyclase gene (dgc) responsible for c-di-GMP synthesis. To determine the role of c-di-GMP signaling in M. t...
ORGANISM(S): Mycobacterium tuberculosis 
2013-10-09 | E-GEOD-37973 | biostudies-arrayexpress
TranscriptomicsSalt/NaCl stress in Desulfovibrio vulgaris Hildenborough
This set of microarray data was used to investigate the effects of D. vulgaris adaptation to excess NaCl. Keywords: stress response, one time point (the mid-log phase for both control and treated cells) Comparison of cells treated with 250 Salt:NaCl to untreated cells at times of mid-log phase min.
ORGANISM(S): Desulfovibrio vulgaris str. Hildenborough 
2010-04-11 | E-GEOD-14343 | biostudies-arrayexpress
TranscriptomicspH stress in Desulfovibrio vulgaris Hildenborough
Using data from microarray experiments, we investigated the effects of excess NaCl on D. vulgaris. Keywords: stress response, time course Comparison of cells treated with pH10 pH to untreated cells at times of 0,120,240,30,60 min.
ORGANISM(S): Desulfovibrio vulgaris str. Hildenborough 
2007-08-31 | E-GEOD-8197 | biostudies-arrayexpress
ProteomicsCharacterization of progressive denaturation and unfolding intermediates of proteins by fast cross-linking using di-ortho-phthalaldehyde
Chemical cross-linking of proteins coupled with mass spectrometry (CXMS) is widely used in protein structural analysis. In this study we develop a new class of non-hydrolyzable amine-selective di-ortho-phthalaldehyde (DOPA) cross-linkers, one of which is DOPA2. Cross-linking of proteins with DOPA2 i...
ORGANISM(S): Staphylococcus Aureus Bos Taurus 
2021-12-20 | PXD030552 |
TranscriptomicsPhenotypic and transcriptional analysis of the osmotic regulator OmpR in Yersinia pestis
Background The osmotic regulator OmpR in Escherichia coli regulates differentially the expression of major porin proteins OmpF and OmpC. In Yersinia enterocolitica and Y. pseudotuberculosis, OmpR is required for both virulence and survival within macrophages. However, the phenotypic and regulatory r...
ORGANISM(S): Yersinia pestis 
2011-10-23 | E-GEOD-26601 | biostudies-arrayexpress
TranscriptomicsGenome-wide expression profiling of the response to D-limonene in Saccharomyces cerevisiae
Metabolic engineering of Saccharomyces cerevisiae for efficient monoterpenes production was mostly restricted by the limited tolerance to these chemicals. Understanding of the molecular mechanisms underlying the tolerance of S. cerevisiae to monoterpenes was essential for the de novo biosynthesis th...
ORGANISM(S): Saccharomyces cerevisiae 
2013-12-23 | E-GEOD-34665 | biostudies-arrayexpress
UnknownCrystal structure of 2-butyl-sulfanyl-4,6-bis-[(E)-4-(di-methyl-amino)-styr-yl]pyrimidine.
Not available
S-EPMC4719932 | biostudies-literature
UnknownAncient DNA reveals genetic connections between early Di-Qiang and Han Chinese.
Not available
S-EPMC5716020 | biostudies-literature
UnknownSystematic Analysis of c-di-GMP Signaling Mechanisms and Biological Functions in Dickeya zeae EC1.
Not available
S-EPMC7733949 | biostudies-literature
UnknownCyclic di-GMP modulates sessile-motile phenotypes and virulence in Dickeya oryzae via two PilZ domain receptors.
Not available
S-EPMC9104268 | biostudies-literature
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