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MetabolomicsMetabolomic Profiling of Mice Serum during Toxoplasmosis Progression Using Liquid Chromatography-Mass Spectrometry
Better understanding of the molecular changes associated with disease is essential for identifying new routes to improved therapeutics and diagnostic tests. The aim of this study was to investigate the dynamic changes in the metabolic profile of mouse sera during T. gondii infection. We carried out ...
2017-01-25 | MTBLS216 | MetaboLights
MetabolomicsGlobal Metabolomic Profiling of Mice Brains following Experimental Infection with the Cyst-Forming Toxoplasma gondii
The interplay between the Apicomplexan parasite Toxoplasma gondii and its host has been largely studied. However, molecular changes at the metabolic level in the host central nervous system and pathogenesis-associated metabolites during brain infection are largely unexplored. We used a global metabo...
2017-01-27 | MTBLS217 | MetaboLights
UnknownCD24 genetic variants contribute to overall survival in patients with gastric cancer.
Not available
S-EPMC4735012 | biostudies-literature
ProteomicsUrine proteomics for profiling of mouse toxoplasmosis using liquid chromatography tandem mass spectrometry analysis
Toxoplasma gondii is an obligate intracellular parasite that can cause severe toxoplasmosis in humans and animals. Although T. gondii infection can disrupt the host's transcription, translation, metabolism and cause kidney damage, the mechanism remains largely unknown.By using a label-free proteomic...
ORGANISM(S): Mus Musculus Mus <mouse, Genus> 
2020-11-10 | PXD022458 |
ProteomicsProteomics analyses of acute kidney injury in a rat exertional heat stroke model
A rat model of AKI caused by EHS was established, and the reliability of the model was evaluated by HE staining and biochemical assays. The expression of kidney tissue proteins in the EHS rats was analyzed using label-free liquid chromatography–tandem mass spectrometry.
ORGANISM(S): Rattus Rattus 
PXD041808 |
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