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ProteomicsRegulation of the Endocytosis and Prion Chaperoning Machineries by Yeast E3 Ubiquitin Ligase Rsp5 as Revealed by Orthogonal Ubiquitin Transfer
Attachment of the ubiquitin (UB) peptide to proteins via the E1-E2-E3 enzymatic machinery regulates diverse biological pathways, yet identification of the substrates of E3 UB ligases remains a challenge. We overcame this challenge by constructing an “orthogonal UB transfer (OUT) cascade with yeast E...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-10-13 | PXD023688 | Pride
Ubiquitin Lc-ms/ms 
UnknownBioinformatic Analyzes of the Association Between Upregulated Expression of JUN Gene via APOBEC-Induced FLG Gene Mutation and Prognosis of Cervical Cancer.
Not available
S-EPMC9058067 | biostudies-literature
UnknownTranscription factor c-Jun modulates GLUT1 in glycolysis and breast cancer metastasis.
Not available
S-EPMC9730598 | biostudies-literature
UnknownJUN mediates glucocorticoid resistance by stabilizing HIF1a in T cell acute lymphoblastic leukemia.
Not available
S-EPMC10661119 | biostudies-literature
UnknownStructural insights into catalysis and dimerization enhanced exonuclease activity of RNase J.
Not available
S-EPMC4477667 | biostudies-literature
MetabolomicsDiagnostic Potential of Plasma IgG N-glycans in Discriminating Thyroid Cancer from Benign Thyroid Nodules and Healthy Controls

BACKGROUND: Novel biomarkers are urgently needed to distinguish between benign and malignant thyroid nodules and detect thyroid cancer in the early stage. The associations between serum IgG N-glycosylation and thyroid cancer risk have been revealed. We aimed to explore the potent...

2021-09-01 | MTBLS2935 | MetaboLights
UnknownsiRNA-targeted inhibition of growth hormone receptor in human colon cancer SW480 cells.
Not available
S-EPMC3848161 | biostudies-literature
UnknownHepatic c-Jun regulates glucose metabolism via FGF21 and modulates body temperature through the neural signals.
Not available
S-EPMC6358569 | biostudies-literature
UnknownTargeting c-Jun orchestrates heat stroke-induced myocardial injury and reveals its biomarker potential.
Not available
S-EPMC12646939 | biostudies-literature
TranscriptomicsmicroRNA expression profiling of CML and normal quiescent cells.
Chronic myeloid leukaemia (CML) is a clonal haemopoietic stem cell (HSC) disorder associated with the BCR-ABL oncogene, which encodes a constitutively active tyrosine kinase. We have demonstrated the existence of CML HSC which are resistant to the tyrosine kinase inhibitors (TKI). We have hypothesis...
ORGANISM(S): Homo sapiens 
2018-01-12 | E-MTAB-3220 | biostudies-arrayexpress
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