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TranscriptomicsmicroRNA expression profiling of CML and normal quiescent cells.
Chronic myeloid leukaemia (CML) is a clonal haemopoietic stem cell (HSC) disorder associated with the BCR-ABL oncogene, which encodes a constitutively active tyrosine kinase. We have demonstrated the existence of CML HSC which are resistant to the tyrosine kinase inhibitors (TKI). We have hypothesis...
ORGANISM(S): Homo sapiens 
2018-01-12 | E-MTAB-3220 | biostudies-arrayexpress
UnknownAccelerated Photogenerated Charge Separation Driven Synergistically by the Interfacial Electric Field and Work Function in Z-Scheme Zn-Ni<sub>2</sub>P/G-C<sub>3</sub>N<sub>4</sub> for Efficient Photocatalytic Hydrogen Evolution.
Not available
S-EPMC12561414 | biostudies-literature
UnknownA dynamic graph Hawkes process based on linear complexity self-attention for dynamic recommender systems
Not available
S-EPMC10280484 | biostudies-literature
ProteomicsSpatially resolved top-down proteomics of tissue sections based on a microfluidic nanodroplet sample preparation platform
We demonstrate spatially resolved top-down proteomics (TDP) for proteoform identification and quantification from small sections of rat brain. We used the nanoPOTS (nanodroplet Processing in One pot for Trace Samples) platform, further improving the sample preparation by adding benzonase in the extr...
ORGANISM(S): Rattus Norvegicus (ncbitaxon:10116) Homo Sapiens (ncbitaxon:9606) 
2022-03-30 | MSV000089163 | MassIVE
UnknownEpidemiological Characteristics and Spatiotemporal Analysis of Occupational Noise-Induced Deafness From 2006 to 2022 in Guangdong, China: Surveillance Study.
Not available
S-EPMC11623259 | biostudies-literature
UnknownJWA loss promotes cell migration and cytoskeletal rearrangement by affecting HER2 expression and identifies a high-risk subgroup of HER2-positive gastric carcinoma patients.
Not available
S-EPMC5095045 | biostudies-literature
ProteomicsSoluble SORLA enhances neurite outgrowth and regeneration through activation of EGFR and MAPK pathways
SORLA is a type I transmembrane component associated with Alzheimers disease (AD) risk. Although SORLA is abundantly expressed in neurons, physiological roles for SORLA remain yet unclear. Here, we show that cultured neurons overexpressing SORLA (SORLA TG) feature enhanced neurite length, and accele...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2020-05-12 | MSV000085400 | MassIVE
ProteomicsInterleukin-6 induced ‘acute’ response promotes Th1 anti-tumor immunity in cryo-thermal therapy: shotgun proteomics
Cryo-thermal therapy has been proven to be a promising novel systemic strategy for advanced breast cancer, resulting in higher incidence of tumor regression and enhanced remission of metastasis. The mechanism by which such strategy boosts the anti-tumor activity remains unclear. To gain a system-wid...
ORGANISM(S): Mus musculus (Mouse) 
2016-05-12 | PXD003136 | Pride
Acute phase response Th1 anti-tumor immunity Cryo-thermal therapy Interleukin-6 Parallel reaction monitoring 
ProteomicsRobust dimethyl-based multiplex-DIA doubles single-cell proteome depth via a reference channel
Single-cell proteomics aims to characterize biological function and heterogeneity at the level of proteins in an unbiased manner. It is currently limited in proteomic depth, throughput, and robustness, which we address here by a streamlined multiplexed workflow using data-independent acquisition (mD...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-12-22 | MSV000090956 | MassIVE
TranscriptomicsCpG island methylation data from maternal venous blood and infant cord blood samples
The biological mechanism of cadmium's effects is poorly characterized. This data was generated in order to help better understand the epigenetic role that Cadmium plays. We used the MIRA assay and the Affymetrix Human Promoter 1.0R Array in order to measure methylation levels in promoter regions. 34...
ORGANISM(S): Homo sapiens 
2015-04-17 | E-GEOD-67976 | biostudies-arrayexpress
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