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ProteomicsA Proximity Labeling Strategy Enables Spatial Proteomic Analysis of Inter-organelle Membrane Contacts in Living Cells
Inter-organelle membrane contacts especially mitochondria-endoplasmic reticulum contacts (MERC) conduct important biological functions including exchange of lipids and ions, and modulation of membrane dynamics. Alterations of inter-organelle membrane contacts have been implicated with the pathogenes...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD035801 | Pride
Apex Bifc Merc Proteome 
ProteomicsA Proximity Labeling Strategy Provides Insights into the Composition and Dynamics of mitochondria-lipid droplet contact proteomes
Accumulating studies have shown that mitochondria-lipid droplet (LD) interaction is crucial for maintaining the homeostasis of lipid metabolism in the liver. However, the proteins involved in mitochondria-LD interaction and the functioning mechanism remain largely elusive. Here, we applied a systema...
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD035813 | Pride
Cholesterol Bifc Comparative proteomics Proximity labeling Mitochondria-lipid droplet contact 
ProteomicsProteomic of human plasma and serum-derived EVs
We isolated the high purity extracellular vesicles from human plasma and serum and performed DIA-MS.
ORGANISM(S): Homo Sapiens 
PXD041146 |
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