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ProteomicsProteome-Wide Deconvolution of Drug Targets and Binding Sites by Lysine Reactivity Profiling
Recently, numerous efforts have been devoted to identifying drug targets and binding sites in complex proteomes, which is of great importance in modern drug discovery. In this study, we developed a robust lysine reactivity profiling method to systematically study drug-binding targets and binding sit...
ORGANISM(S): Homo Sapiens 
2023-09-28 | PXD045749 |
UnknownTMEM44-AS1 promotes esophageal squamous cell carcinoma progression by regulating the IGF2BP2-GPX4 axis in modulating ferroptosis.
Not available
S-EPMC10692126 | biostudies-literature
MetabolomicsAuricularia auricula polysaccharides reduce obesity in mice through gut commensal Papillibacter cinnamivorans
Auricularia auricula is a well-known traditional edible and medicial fungus with high nutritional and pharmacological values, as well as metabolic and immunoregulatory properties. However, the exact mechanisms underlying the effects of Auricularia auricula polysaccharides (AAP) on obesity and relate...
2022-09-16 | MTBLS4469 | MetaboLights
UnknownGALNT6 promotes invasion and metastasis of human lung adenocarcinoma cells through O-glycosylating chaperone protein GRP78.
Not available
S-EPMC7214460 | biostudies-literature
UnknownCharacterization of a small-molecule inhibitor targeting NEMO/IKKβ to suppress colorectal cancer growth.
Not available
S-EPMC8904520 | biostudies-literature
ProteomicsAP-MS Raw data of C. burnetii-host PPIs
Fifty-three Coxiella effectors were expressed in HEK-293T cells, and the Strep-tagged Coxiella effectors and the corresponding interacting complex were purified for MS analysis. The LC-MS/MS analyses were performed with an Orbitrap Fusion Tribrid mass spectrometer (Thermo Fisher Scientific) coupled ...
ORGANISM(S): Homo Sapiens 
2022-03-18 | PXD032380 |
ProteomicsSerum proteomics of individuals with MASLD under resistance starch intervention
Searching for baseline proteins that contribute to the individual response to RS intervention
ORGANISM(S): Homo Sapiens 
2025-09-24 | PXD068798 |
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