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TranscriptomicsMicro-array analysis of wild-type BALB/cByJ mice livers against PMLA220V knock-in mice
Study the impact of the most common mutation on the PML protein found in acute promyeocytic leukemia patients resistant to arsenic therapy, which induces a disorganization of PML nuclear bodies, on gene expression.
ORGANISM(S): Mus musculus 
2023-11-29 | E-MTAB-13183 | biostudies-arrayexpress
TranscriptomicsMicro-array analysis of wild-type BALB/cByJ mice livers against PMLA220V knock-in mice
Study the impact of the most common mutation on the PML protein found in acute promyeocytic leukemia patients resistant to arsenic therapy, which induces a disorganization of PML nuclear bodies, on gene expression.
ORGANISM(S): Mus musculus 
2023-11-29 | E-MTAB-12943 | biostudies-arrayexpress
GenomicsGenome wide mapping of long noncoding (lnc) RNAs in hepatic stellate cells
Hepatic stellate cells are the primary cell type responsible for development of fibrosis in chronic liver disease. We used directional RNA sequencing (RNA-seq) and chromatin immunoprecipitation and sequencing (ChIP-seq) to identify the lncRNAs expressed in human HSCs. We also identified the lncRNAs...
ORGANISM(S): Homo sapiens 
2016-03-23 | E-GEOD-68108 | biostudies-arrayexpress
MetabolomicsProtein-metabolite interactomics of carbohydrate metabolism reveal regulation of lactate dehydrogenase

Metabolic networks are interconnected and influence diverse cellular processes. The protein-metabolite interactions that mediate these networks are frequently low affinity and challenging to systematically discover. We developed mass spectrometry integrated with equilibrium dialysis for the disco...

2023-08-07 | MTBLS7237 | MetaboLights
UnknownENU-induced mutation in the DNA-binding domain of KLF3 reveals important roles for KLF3 in cardiovascular development and function in mice.
Not available
S-EPMC3708807 | biostudies-literature
TranscriptomicsTargeted inhibition of the JAK/STAT3 pathway inhibits ovarian carcinoma growth
Ovarian carcinoma (OC) is the fifth leading cause of death among women in the United States. Persistent activation of signal transducer and activator of transcription (STAT3) is frequently detected in OC. STAT3 is activated by Janus family kinases (JAK) via cytokine receptors, growth factor receptor...
ORGANISM(S): Mus musculus 
2015-02-01 | E-GEOD-63092 | biostudies-arrayexpress
UnknownThe Medicago genome provides insight into the evolution of rhizobial symbioses.
Not available
S-EPMC3272368 | biostudies-literature
UnknownA Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers.
Not available
S-EPMC5959730 | biostudies-literature
UnknownSpectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort.
Not available
S-EPMC5984248 | biostudies-literature
UnknownMR-less surface-based amyloid assessment based on 11C PiB PET.
Not available
S-EPMC3888418 | biostudies-literature
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