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We conducted a DIA-based proteomics study for 5 patients with CHD-PBS Syndrome, 5 patients with CHD-NPBS Syndrome, and 5 healthy adults to explore the biomarkers of PBS Syndrome.
ORGANISM(S): Homo Sapiens 
Primary osteoporosis, manifesting as decreased bone mass and increased bone fragility, is a “silent disease” that is often ignored until a bone breaks. Accordingly, it is urgent to develop reliable biomarkers and novel therapeutic strategies for osteoporosis treatment. Here, we identified REGγ as...
ORGANISM(S): Homo Sapiens 
This study deals with discovering biomarkers for the diagnosis of intracranial aneurysm
ORGANISM(S): Homo Sapiens 
As a well-known anti-diabetic drug, metformin has been repurposed for cancer treatment, but drug resistance and tumor metastasis observed recently have challenged its further application. Here, we found that long-term metformin exposure led to metabolic adaptation of HCC cells, which was characteriz...
ORGANISM(S): Homo Sapiens 
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