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UnknownNAD+-boosting agent nicotinamide mononucleotide potently improves mitochondria stress response in Alzheimer's disease via ATF4-dependent mitochondrial UPR.
Not available
S-EPMC11470026 | biostudies-literature
UnknownInhibition of cystathionine β-synthase promotes apoptosis and reduces cell proliferation in chronic myeloid leukemia.
Not available
S-EPMC7870845 | biostudies-literature
UnknownTranscriptional activation of USP16 gene expression by NFκB signaling.
Not available
S-EPMC6937840 | biostudies-literature
UnknownAlpha-lipoic acid alleviates cognitive deficits in transgenic APP23/PS45 mice through a mitophagy-mediated increase in ADAM10 α-secretase cleavage of APP.
Not available
S-EPMC11264788 | biostudies-literature
TranscriptomicsA large-scale clinical study of gene expression response to severe burn injury
To understand the age-dependent response to burn injury, blood samples from pediatric and adult patients were collected at different times after severe burn injury. Gene expression was measured using Affymetrix U133 Plus 2.0 arrays for both patient samples and healthy controls. Time points were binn...
ORGANISM(S): Homo sapiens 
2010-06-16 | E-GEOD-19743 | biostudies-arrayexpress
TranscriptomicsA long noncoding RNA protects the heart from pathological hypertrophy
The role of long noncoding RNA (lncRNA) in adult hearts is unknown; also unclear is how lncRNA modulates nucleosome remodelling. An estimated 70% of mouse genes undergo antisense transcription1, including myosin heavy chain 7 (Myh7), which encodes molecular motor proteins for heart contraction2. Her...
ORGANISM(S): Homo sapiens 
2014-08-05 | E-GEOD-49716 | biostudies-arrayexpress
UnknownDiphthamide deficiency promotes association of eEF2 with p53 to induce p21 expression and neural crest defects.
Not available
S-EPMC11053169 | biostudies-literature
UnknownAn autoimmune pleiotropic SNP modulates IRF5 alternative promoter usage through ZBTB3-mediated chromatin looping.
Not available
S-EPMC9984425 | biostudies-literature
ProteomicsMuscular lactate modulates phase transition-driven lactate body secretion to induce liver fibrosis during long-term overtraining
Exercise, as the fundamental therapy for metabolic diseases, often exhibits a dose-dependent fashion. However, the adverse effects of overtraining and underlying mechanisms remain unclear. Here, we show that long-term overtraining induces hepatic fibrosis in humans and mice. Mechanistically, excessi...
ORGANISM(S): Mus Musculus 
PXD052424 |
ProteomicsProteomics comparison of protein changes in H1299 cell before and after resistance to cdk4/6 inhibitors
This is the raw proteomics data of H1299 cell before and after resistance to cdk4/6 inhibitors
ORGANISM(S): Homo Sapiens 
PXD042216 |
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