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ProteomicsDefining proximity proteomics of Histone modifications by antibody-mediated protein A-APEX2 labeling
Proximity labeling catalyzed by promiscuous enzymes, such as APEX2, has emerged as a powerful approach to characterize multiprotein complexes and protein–protein interactions. However, current methods depend on the expression of exogenous fusion proteins and cannot be applied to identify proteins su...
ORGANISM(S): Mus musculus (Mouse) 
2023-07-12 | PXD028063 | Pride
Proximity labeling  post-translationally  amapex  modified histones 
ProteomicsClinical proteomics analysis using Data Independent Acquisition-Mass Spectrometry (DIA-MS) identified classifiers for molecular characterization of Lymphoma
In this study, we conducted a proteomics analysis on 109 fresh-frozen lymph node samples from clinical patients, covering a comprehensive suite of lymphoma subtypes including B-NHL, T-NHL, HL, Lymphadenitis, Tumor metastatic lymph node (TLN), and Non-neoplastic lymph node (TNM: N0).
ORGANISM(S): Homo Sapiens 
2020-01-15 | PXD017096 |
ProteomicsSpatially resolved proteomic mapping in skin organoid for hair follicle development
Hair follicle development is a complex, highly regulated process involving interactions between epithelial and mesenchymal cells. However, the specific molecular mechanisms and important biological processes of hair follicle development remain poorly understood. In this study, we applied spatially r...
ORGANISM(S): Homo Sapiens 
2025-04-08 | PXD062716 |
ProteomicsThe rice aspartyl-tRNA synthetase YLC3 regulates amino acid homeostasis and chloroplast development under low temperature
Aminoacyl tRNA synthetases are key enzymes in protein synthesis, attaching the proper amino acid to the corresponding tRNA to make protein. However, their roles in regulating plant growth and development still remain elusive. Here we reported a rice thermo-sensitive mutant yellow leaf chlorosis3 (yl...
ORGANISM(S): Oryza Sativa 
2022-02-08 | PXD031497 |
ProteomicsOligomerization of PRMT1 Regulated RNA-Binding Protein Cascade Promotes Pancreatic Ductal Adenocarcinoma
PRMT1 is the predominant type I protein arginine methyltransferase responsible for generating monomethylarginine and asymmetric dimethylarginine (MMA and ADMA) in various protein substrates. It regulates numerous biological processes, including RNA metabolism, mRNA splicing, DNA damage repair, and c...
ORGANISM(S): Homo Sapiens 
2025-03-12 | PXD061743 |
ProteomicsIdentification of circEZH2_005-interacting proteins by mass spectrometry
liquid chromatography tandem mass spectrometry is used to identificate of the circEZH2_005-Interacting protein pulled down by circEZH2_005 junction probe with protein extracts from Intestinal crypt cells.
ORGANISM(S): Mus Musculus 
2023-03-17 | PXD040925 |
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