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Archaea are differentiated from the other two domains of life by their biomolecular characteristics. One such characteristic is the unique structure and composition of their lipids. Characterization of the whole set of lipids in a biological system (the lipidome) remains technologically challengi...

2021-12-16 | MTBLS3714 | MetaboLights

Depression is an individual risk factor for poor prognosis in patients with heart failure (HF). Recent studies show that gut microbiota and metabolites have critical role in comorbid HF and depressive symptoms. We recruited 95 subjects including 35 HF patients with depressive symptoms (HF-DS), 36...

2023-10-23 | MTBLS8183 | MetaboLights
1, Using mRNA-Seq to get expression profiling of rrp6l1-2 mutant and Col-0 wild-type (WT); 2,Using MethylC-Seq to provide single-base resolution of DNA methylation status in rrp6l1-2 mutant; 3, Using small RNA-Seq(sRNA-Seq) to get small RNA profiling of rrp6l1-2 and WT mRNA-Seq: 2 samples examined, ...
ORGANISM(S): Arabidopsis thaliana 
Host cell lipids play a pivotal role in the pathogenesis of respiratory virus infection. However, a direct comparison of the lipidomic profile of influenza virus and rhinovirus infections is lacking. In this study, we first compared the lipid profile of influenza virus and rhinovirus infection in a ...
2022-11-15 | MTBLS2352 | MetaboLights
Using MethylC-Seq to provide single-base resulution of DNA methylation status in ibm1-4 mutant 1 sample examined, ibm1-4 mutant
ORGANISM(S): Arabidopsis thaliana 
1, Using mRNA-Seq to get expression profiling of asi1-1 mutant and WT; 2, Using MethylC-Seq to provide single-base resulution of DNA methylation status in asi1-1 mutant mRNA-Seq: 2 samples examined, Col-0 wild-type with 35S-SUC2 transgene(termed as WT) and asi1-1 mutant (Col-0 background with 35S-SU...
ORGANISM(S): Arabidopsis thaliana 

Apicomplexan parasite growth and replication relies on nutrient acquisition from host cells, in which intracellular multiplication occurs, yet the mechanisms that underlie the nutrient salvage remain elusive. Numerous ultrastructural studies have documented a plasma membrane invagination with a d...

2023-04-19 | MTBLS7006 | MetaboLights
Using MethylC-Seq to provide single-base resolution of DNA methylation status in ago6-2, ago4-6 and ago4-6 ago6-2 double mutants MethylC-Seq: 3 mutants examined, ago6-2, ago4-6 single mutant and ago4-6 ago6-2 double mutants
ORGANISM(S): Arabidopsis thaliana 
Using whole genome bisulfite sequencing to provide single-base resulution of DNA methylation status in ros1, idm1, and rdd mutants and identify hypermethylated regions comparing to wild type Arabidopsis plants. Examination of 3 different mutants' methylome. 8 samples (3 mutants, 1 WT, each has two b...
ORGANISM(S): Arabidopsis thaliana 
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