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ProteomicsNeofusiccocum parvum mycelium LC-MS/MS
TMT quantitative proteome of BH01 and BH03 of two Neofusiccocum parvum strains under different culture conditions
ORGANISM(S): Neofusicoccum Parvum 
2022-06-03 | PXD034277 |
ProteomicsUbiquitin Ligase Enzyme FANCL Inhibits Peste des petits ruminants Virus Replication by Inducing Type I Interferon Production through Promoting Phosphorylation of TBK1
Peste des petits ruminants virus (PPRV) infection causes highly contagious and severe disease in domestic and wild ruminants. It is widely reported that PRRV infection causes considerable innate immunosuppression in its host and promotes viral replication. However, how does the host rescue the innat...
ORGANISM(S): Ovis aries 
2021-07-26 | PXD022271 | Pride
Peste des petits ruminants virus  quantitative proteomics  fancl  innate immune response  tbk1 
ProteomicsThe insufficient activation of RIG-I-like signaling pathway in IBRS-2 cells contributes to highly efficient replication of porcine picornaviruses
Seneca Valley Virus (SVV) or commonly known as Senecavirus A (SVA), is one of picornavirus that is associated with vesicular disease and neonatal mortality in swine herds. However, the pathogenesis of SVV remains largely elusive. Our previous study found that SVV replicates extremely faster in porci...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2021-10-05 | PXD024002 | Pride
Senecavirus a  foot-and-mouth disease virus  rig-i like receptor signaling pathway  interferon  antiviral response 
ProteomicsThe insufficient activation of RIG-I-like signaling pathway in IBRS-2 cells contributes to highly efficient replication of porcine picornaviruses
Seneca Valley Virus (SVV) or commonly known as Senecavirus A (SVA), is one of picornavirus that is associated with vesicular disease and neonatal mortality in swine herds. However, the pathogenesis of SVV remains largely elusive. Our previous study found that SVV replicates extremely faster in porci...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2021-10-05 | PXD024003 | Pride
Senecavirus a  foot-and-mouth disease virus  rig-i like receptor signaling pathway  interferon  antiviral response 
ProteomicsPeste des petits ruminants virus nucleocapsid protein interacts with PACT and induces stress granule to promote viral replication
Stress granules (SGs) formation is a conserved cellular strategy to reduce stress-related damage regulating cell survival. A Mass spectrometry-based profiling of the interactome of PPRV N protein revealed that PPRV N interacted with PACT to regulate the assembly of SGs. N protein inhibited the inter...
ORGANISM(S): Homo Sapiens 
2022-12-27 | PXD039104 |
ProteomicsQuantitative Proteomics Analysis with TMT Markers
Using TMT-labeled quantitative protein technique, we quantitatively analyzed the proteomes of three different resistant Bambusa pervariabilis × Dendrocalamopisis grandis under four different treatments: pathogenic fungi, pathogenic toxin, pathogenic fungi plus toxin and sterile water, and screened o...
ORGANISM(S): Bambusa Pervariabilis Bambusa Grandis 
2019-06-24 | PXD014363 |
ProteomicsARIH1 Signaling Promotes Anti-tumor Immunity by Targeting PD-L1 for Proteasomal Degradation
We find EGFR inhibitors promote PD-L1 ubiquitination and proteasomal degradation following GSK3α-mediated phosphorylation of Ser279/Ser283.
ORGANISM(S): Homo Sapiens 
2021-03-01 | PXD024452 |
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