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MetabolomicsFasudil may alleviate alcohol-induced astrocyte damage by modifying lipid metabolism, as determined by metabonomics analysis

Alcohol dependence is a chronic, relapsing encephalopathy characterized by compulsive craving for alcohol, loss of control over alcohol use, and the presence of negative emotions and physical discomfort when alcohol is unavailable. Harmful use of alcohol is one of the greatest risk factors for de...

2023-05-15 | MTBLS5071 | MetaboLights
MetabolomicsChromosome‐level genome of Camellia lanceoleosa provides a valuable resource for understanding genome evolution and self‐incompatibility

The section Oleifera (Theaceae) has attracted attention for the high levels of unsaturated fatty acids found in its seeds. Here, we report the chromosome-scale genome of the sect. Oleifera using diploid wild Camellia lanceoleosa with a final size of 3.00 Gb and an N50 s...

2022-07-14 | MTBLS3769 | MetaboLights
GenomicsCharles R. Bronfman Institute for Personalized Medicine (IPM) BioBank Genome Wide Association Study of Cardiovascular, Renal and Metabolic Phenotypes

The Institute for Personalized Medicine (IPM) Biobank Project is a consented, EMR-linked medical care setting biorepository of the Mount Sinai Medical Center (MSMC) drawing from a population of over 70,000 inpatients and 800,000 outpatient visits annually. MSMC serves diverse local commun...

phs000388.v1.p1 | EGA
MetabolomicsMechanism of interventional effect and targets of Zhuyu Pill in regulating and suppressing colitis and cholestasis

Zhuyu pill (ZYP) is a traditional Chinese medicine prescription composed of two drugs, Coptis chinensis Franch. and Tetradium ruticarpum (A. Jussieu) T. G. Hartley, and is commonly used in the clinical treatment of diseases of the digestive system. However, the mechanism underly...

2022-11-02 | MTBLS4980 | MetaboLights
TranscriptomicsRNase ZS1-mediated UbL40 mRNA decay controls thermo-sensitive genic male sterility in rice.
Male sterility is an important trait in hybrid crop breeding. Thermo-sensitive genic male sterility (TGMS) lines, which are male-sterile at restrictive (high) temperatures but convert to male-fertile at permissive (low) temperatures, have been widely utilized in two-line hybrid rice breeding3. Howev...
ORGANISM(S): Oryza sativa Indica Group 
2014-09-11 | E-GEOD-42314 | biostudies-arrayexpress
ProteomicsOne-Pot Isotope Dilution PRM for Quantitative Protein Heterogeneity in Red Blood Cells
Single cell and low-input cell proteomics to measure cellular heterogeneity remains experimental and requires further refinement for routine application. This study aimed to build on previous protocols to assess the utility of targeted proteomics for measuring heterogeneity in red blood cells (RBCs)...
ORGANISM(S): Homo Sapiens 
2024-02-06 | PXD030875 | panorama
ProteomicsTumor-specific circRNAs elicit anti-tumor immune response via encoding cryptic antigenic peptides
Mass spectrometry for HLA class I (HLA-I) peptidome of human breast cancer samples identified an HLA-I binding peptide encoded by circRNA.
ORGANISM(S): Homo Sapiens Mus Musculus 
2023-12-21 | PXD041427 |
ProteomicsMolecular Phenomics of the Gut Ecosystem in COVID-19 Patients
Stool metaproteomics of COVID-19 patients and healthy subjects to discover host and microbial protein alterations of gut ecosystem.
ORGANISM(S): Homo Sapiens 
2020-12-14 | PXD023099 |
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