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UnknownrMVP: A Memory-efficient, Visualization-enhanced, and Parallel-accelerated Tool for Genome-wide Association Study.
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S-EPMC9040015 | biostudies-literature
TranscriptomicsTwo Supporting Factors Greatly Improve the Efficiency of Human iPS Cell Generation
Human fibroblasts can be induced into pluripotent stem cells (iPS cells), but the reprogramming efficiency is quite low. Here, we screened a panel of candidate factors in the presence of OCT4, SOX2, KLF4 and c-MYC in an effort to improve the reprogramming efficiency from human adult fibroblasts. We ...
ORGANISM(S): Homo sapiens 
2008-11-06 | E-GEOD-12922 | biostudies-arrayexpress
ProteomicsQuantitative proteomics of EDB-treated APP/PS1 mice
Hippocampal proteins were extracted from the brain tissues of APP+SA and APP+EDB mice. The proteomics experiments and subsequent bioinformatics analysis were supported by OE Biotech Co..
ORGANISM(S): Mus Musculus 
2024-08-13 | PXD054845 |
ProteomicsEnergy sensor AMPK gamma regulates translation via phosphatase PPP6C independent of AMPK alpha
In this project, SILAC-based quantitative proteomics approach was applied for phosphoproteomics analysis. The light samples were treated with ddH2O as control group, and the medium samples labeled by 2D2 of lysine (K4) and 13C6 of arginine (R6) were treated with 2DG, while the heavy samples labeled ...
ORGANISM(S): Homo Sapiens 
2022-11-08 | PXD038034 |
ProteomicsA chaperone-like function of FUS ensures TAZ condensates dynamics and transcriptional activation
The Hippo pathway plays important roles in organ development, tissue homeostasis, and tumor growth, and its downstream effector TAZ is a transcriptional coactivator that promotes target gene expression through the formation of biomolecular condensates. However, the mechanisms that regulate the biop...
ORGANISM(S): Homo Sapiens 
2023-02-17 | PXD040257 |
ProteomicsProteomics of the Gastric cancer Response to Chemotherapy
Herein, we set out to investigate the responses to first-line therapies (DOS, XELOX, and anti-HER2-based therapies) for GC through a comprehensive proteomic analysis. We constructed a GC cohort that covered three clinical therapy subcohorts, including a DOS subcohort (44 patients treated with DOS th...
ORGANISM(S): Homo Sapiens 
2022-09-09 | PXD024255 |
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