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ProteomicsExplore the lactation function of Protein phosphorylation sites in goat mammary tissues by phosphoproteome
Background: Protein phosphorylation plays an important role in lactation. Differentially modified phosphorylation sites between peak lactation (PL, 90 days postpartum) and late lactation (LL, 280 days postpartum) were investigated using an integrated approach, namely, liquid chromatography with tand...
ORGANISM(S): Capra hircus (Goat) 
2022-02-17 | PXD026437 | Pride
Phosphoproteome  lactation  irs1  β-casein  triglycerides  goat 
TranscriptomicsTranscription profiling of human T98G cells during cell cycle in T98G
The mammalian Retinoblastoma (RB) family including pRB, p107, and p130 represses E2F target genes through mechanisms that are not fully understood. In D. melanogaster, RB-dependent repression is mediated in part by the multisubunit protein complex Drosophila RBF, E2F, and Myb (dREAM) that contains h...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-8537 | biostudies-arrayexpress
ProteomicsEnhancer DNA pull-down of proteins extracted from PA2 tissue of mouse E11.5 embryos
Enhancers, through the combinatorial action of transcription factors (TFs), dictate both the spatial specificity and the levels of gene expression, and their aberrations can result in diseases. While HMX1 downstream enhancer is associated to ear malformations, the mechanisms underlying bilateral con...
ORGANISM(S): Mus musculus (Mouse) 
2025-04-28 | PXD063373 | Pride
Dna pull-down Mouse e11.5 embryos 
ProteomicsSC-43 Inhibits Methicillin-resistant Staphylococcus aureus Through Inhibition of Heme Biosynthesis
SC-43 inhibits the key enzyme coproporphyrin ferrochelatase (CpfC) of the coproporphyrin-dependent (CPD) heme synthesis pathway and interferes with the bacterial porphyrin metabolism.
ORGANISM(S): Staphylococcus Aureus 
2026-01-22 | PXD073397 |
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