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ProteomicsHIRA and dPCIF1 coordinately establish totipotent chromatin and control orderly ZGA in Drosophila embryos
In order to understand the molecular mechanism underlying the action of dPCIF1 in early embryos, we carried out co-immunoprecipitation (co-IP) assays followed by mass spectroscopic analysis using dPCIF1GFP-KI early embryos (0.5–1.5 hours). In this assay, we identified a large number of dPCIF1-intera...
ORGANISM(S): Drosophila Melanogaster 
2024-01-18 | PXD048659 |
ProteomicsIntegrated Proteomics and Metabolomics Link Acne to the Action Mechanisms of Cryptotanshinone Intervention
The label-free methods of proteomic combined with metabolomics were applied to explore the mechanisms of Cryptotanshinone intervention in rats with acne. These results propose action mechanisms for the use of CPT in acne, as a safe and potential new drug.
ORGANISM(S): Rattus Rattus 
2021-07-12 | PXD027219 |
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