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ProteomicsQuantitative Proteomic Atlas of Ubiquitination in Hepatocellular Carcinoma
Ubiquitination plays a critical role in human hepatocellular carcinoma (HCC) genesis and metastasis, but how these processes affect systemic ubiquitinome still remains unclear. In this study, our dataset of around 12,000 diGly modified sites was identified providing a valuable insight into HCC. We f...
ORGANISM(S): Homo Sapiens 
2020-04-14 | PXD011895 |
ProteomicsQuantitative proteomic data of hepatocellular carcinoma
Ubiquitination plays a critical role in human cancer genesis and metastasis, but how the systemic ubiquitinome changes during these processes remains unclear. In this study, our dataset of approximately 12,000 identified ubiquitinated sites provided valuable insight into human hepatocellular carcino...
ORGANISM(S): Homo Sapiens 
2020-04-16 | PXD018593 |
MetabolomicsSensing Ceramides by CYSLTR2 and P2RY6 to Aggravate Atherosclerosis

Recent evidence shows elevated circulating long-chain ceramide levels predicts atherosclerotic cardiovascular disease (ASCVD) independently of cholesterol. Although targeting ceramides signaling may provide therapeutic benefits beyond the treatment of hypercholesterolemia, the underlying mechanis...

2025-04-15 | MTBLS11925 | MetaboLights
Proteomicsdevelopment of prognostic biomarkers for HBV-related acute-on-chronic liver failure
development of prognostic biomarkers for HBV-related acute-on-chronic liver failure
ORGANISM(S): Homo Sapiens 
2020-03-07 | PXD017928 |
ProteomicsIdentification of ANXA1 as A Novel Upstream Negative Regulator of Notch1 Function in AML
Abnormal Notch1 expression has an important role in tumorigenesis. However, upstream control mechanisms for Notch1 are still insufficiently understood. Acute myeloid leukemia (AML) is one of the most common and lethal blood malignancies with limited possibilities for treatment. Thus, new therapeutic...
ORGANISM(S): Homo Sapiens 
2024-10-03 | PXD056593 |
ProteomicsRNA-Pull down and MS for Snhg3
To screen Snhg3-binding proteins using-RNA Pull down and MS
ORGANISM(S): Mus Musculus 
2023-01-17 | PXD039526 |
ProteomicsDDX5-sIL-36R in keratinocytes controls skin inflammation
The DEAD-box (DDX) proteins function in diverse cellular processes including RNA alternative splicing, and are linked to immune-mediated diseases. However, little is known about the roles of DDXs in skin inflammatory diseases. Here, we show that DDX5, one of the founding members of the DDX RNA helic...
ORGANISM(S): Homo Sapiens 
2020-09-09 | PXD021379 |
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