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TranscriptomicsLactate modulates gene expression in human mesenchymal stem cells
Wound healing is associated with high rates of cell replication and lactate accumulation even under normoxic and hyperoxic conditions. Lactate accounts for various effects in tissue regeneration, such as collagen synthesis, angiogenesis, modulation of cytokine patterns and as recently shown for stem...
ORGANISM(S): Homo sapiens 
2010-05-15 | E-GEOD-11458 | biostudies-arrayexpress
TranscriptomicsInfluence of exhaustive endurance exercise on gene expression in peripheral blood
cDNA microarray screening for gene expression changes in peripheral blood of eight half-marathon runners before (time point 0), immediately (time point 1) after and 24 h (time point 2) after exercise for details see publication: ...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-2532 | biostudies-arrayexpress
TranscriptomicsLactate influences the gene expression profile of human mesenchymal stem cells (hMSC) in a dose dependent manner
Wounds, especially non healing wounds are characterised by elevated tissue lactate concentrations. Lactate is known for being able to stimulate collagen synthesis and vessel growth. Lately it has been shown that lactate, in vivo, plays an important role in homing of stem cells. With this work we aim...
ORGANISM(S): Homo sapiens 
2013-01-09 | E-GEOD-40205 | biostudies-arrayexpress
TranscriptomicsClock genes in human oral mucosa
Circadian rhythms are daily oscillations of multiple biological processes driven by endogenous clocks. Imbalance of these rhythms has been associated with cancerogenesis in humans. To further elucidate the role of the circadian clock in cellular growth control, tumor suppression and cancer treatment...
ORGANISM(S): Homo sapiens 
2010-05-16 | E-GEOD-11469 | biostudies-arrayexpress
TranscriptomicsMesenchymal stem cell labelings with ferritin
Mesenchymal stem cells (MSC) omplexed to different transfection agents (R60, R200, DOSPER, jetPei, Pulsin). Two MSC populations (h21 and h24) and two passages (P2 and P4) were tested with different labelings. In a direct design experiment each sample was compared to its unlabeled control sample. Key...
ORGANISM(S): Homo sapiens 
2010-05-16 | E-GEOD-11470 | biostudies-arrayexpress
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