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TranscriptomicsInfiltrating monocyte-derived macrophages and resident kupffer cells display different ontogeny and functions in acute liver injury
Molecular profiling of infiltrating monocyte-derived macrophages versus resident kupffer cells following acute liver injury The liver has a remarkable capacity to regenerate after injury; yet, the role of macrophages (MF) in this process remains controversial mainly due to difficulties in distinguis...
ORGANISM(S): Mus musculus 
2014-08-01 | E-GEOD-55606 | biostudies-arrayexpress
TranscriptomicsMacrophage-restricted Interleukin-10 receptor-, but not IL-10 deficiency causes severe spontaneous colitis
Interleukin-10 (IL-10) is a pleiotropic anti-inflammatory cytokine produced and sensed by most hematopoietic cells. Genome wide association studies and experimental animal models point at a central role of the IL-10 axis in Inflammatory Bowel Diseases. Here we investigated the importance of intestin...
ORGANISM(S): Mus musculus 
2014-05-09 | E-GEOD-56444 | biostudies-arrayexpress
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