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UnknownInborn Errors of RNA Lariat Metabolism in Humans with Brainstem Viral Infection.
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S-EPMC5886375 | biostudies-literature
TranscriptomicsDegradation of cellular miR-27 by a novel, highly abundant viral transcript is important for efficient virus replication in vivo.
Cytomegaloviruses express large amounts of viral miRNAs during lytic infection, yet, they only modestly alter the cellular miRNA profile. The most prominent alteration upon lytic murine cytomegalovirus (MCMV) infection is the rapid degradation of the cellular miR-27a and miR-27b. Here, we report tha...
ORGANISM(S): Mus musculus 
2012-03-01 | E-GEOD-34475 | biostudies-arrayexpress
TranscriptomicsReal-time transcriptional profiling of cellular and viral gene expression during lytic cytomegalovirus infection
During viral infections cellular gene expression is subject to rapid alterations induced by both viral and antiviral mechanisms. In this study, we applied metabolic labeling of newly transcribed RNA with 4-thiouridine (4sU-tagging) to dissect the real-time kinetics of cellular and viral transcriptio...
ORGANISM(S): Mus musculus 
2013-02-14 | E-GEOD-35833 | biostudies-arrayexpress
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