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ProteomicsCharacterization of extracellular vesicles from Bothrops jararaca snake venom
Venoms are important evolutionary keys and innovation for several animal taxons., including snakes. Their use is specially related to feed, predation and defense. Snake venoms are composed mainly by free secreted proteins, about 98%, and stored in the lumen of the venom gland, where they are process...
ORGANISM(S): Bothrops jararaca (Jararaca) (Bothrops jajaraca) 
2023-03-10 | PXD037375 | Pride
Extracellular vesicles Snake venom 
ProteomicsProteomic analysis of HCC-1954 and MCF-7 cell lines highlights crosstalk between αvβ1 integrin, E-cadherin and HER-2
Overexpression of human epidermal growth factor receptor 2 (HER-2) occurs in 20% of all breast cancer subtypes, those that present the worst prognostic outcome through a very invasive and aggressive tumour. HCC-1954 (HER-2+) is a highly invasive, metastatic cell line whereas MCF-7 is mildly aggressi...
ORGANISM(S): Homo sapiens (Human) 
2022-10-14 | PXD023876 | Pride
Hcc-1954 Membrane proteins Her-2 Breast cancer Mcf-7 Proteome 
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