Sort   by:  
 Page size 
ProteomicsInhibition of the mitochondrial disulfide relay system impairs liver cancer cell proliferation
Augmenter of liver regeneration (ALR) is a critical multi-isoform protein with its longer isoform, located in the mitochondrial intermembrane space, being part of the mitochondrial disulfide relay system (DRS). Upregulation of ALR was observed in multiple forms of cancer, among them hepatocellular c...
ORGANISM(S): Rattus rattus (Black rat) 
2022-02-17 | PXD026695 | Pride
Mitochondria Heme Hcc Disulfide relay Iron 
ProteomicsIron Toxicity targeting mitochondrial Iron-Sulfur cluster enzymes
Unregulated nutritional iron absorption in hereditary hemochromatosis causes its overload, especially in liver. While this may lead to severe pathology, intriguingly, it may also frequently go unrecognized. Indeed, profound iron loading in hemochromatosis Hfe knockout mice and hemochromatosis Huh7 h...
ORGANISM(S): Homo sapiens (Human) 
2026-09-28 | PXD070837 | Pride
Iron-sulfur cluster enzymes Mitochondria Hemochromatosis Trace metals Methanobactin Liver Iron overload 
TranscriptomicsIdentification of proliferative and mature β-cells in the islet of Langerhans
Insulin-dependent diabetes is a complex multifactorial disorder characterized by loss or dysfunction of β-cells. Pancreatic β-cells differ in size, glucose responsiveness, insulin secretion and precursor cell potential1-5, thus understanding the mechanisms underlying this functional heterogeneity ...
ORGANISM(S): Mus musculus 
2016-06-02 | E-GEOD-68853 | biostudies-arrayexpress
Sort   by:  
 Page size