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TranscriptomicsCandida albicans SFL1 and SFL2 transcriptomics
Expression profiling of C. albicans homozygous sfl1 and sfl2 mutants expressing (sfl1-CaEXP-SFL1-HA3, sfl2-CaEXP-SFL2-HA3) or not (sfl1-CaEXP, sfl2-CaEXP, vector only control) SFL1-HA3 and SFL2-HA3, respectively, under hyphae-inducing conditions (Lee's medium at 37 degrees C).
ORGANISM(S): Candida albicans 
2013-06-15 | E-MEXP-3779 | biostudies-arrayexpress
TranscriptomicsIdentification of the Candida albicans Cap1p regulon (Cap1-CSE-HA and Cap1-HA complete datasets)
Cap1p, a transcription factor of the basic region-leucine zipper family, regulates oxidative stress response (OSR) in Candida albicans. Alteration of its C-terminal cysteine-rich domain (CRD) results in Cap1p nuclear retention and transcriptional activation. To better understand the function of Ca...
ORGANISM(S): Candida albicans 
2010-05-18 | E-GEOD-15104 | biostudies-arrayexpress
TranscriptomicsTargeted changes of cell wall proteome influence Candida albicans ability to form single- and multi-strain biofilms.
Biofilm formation is an important virulence trait of the pathogenic yeast Candida albicans. Large-scale genetics strategies aimed at identifying genes involved in biofilm development are hampered by lack of a complete sexual cycle in this diploid yeast in addition to the tedious generation of homozy...
ORGANISM(S): Candida albicans 
2014-03-31 | E-GEOD-48647 | biostudies-arrayexpress
TranscriptomicsIdentification of the Candida albicans CAP1 regulon
Cap1p, a transcription factor of the basic region-leucine zipper family, controls the oxidative stress response in Candida albicans. It was shown that alteration of the C-terminal cysteine-rich domain (CRD) of Cap1p results in nuclear retention and constitutive transcriptional activation. To further...
ORGANISM(S): Candida albicans 
2010-05-18 | E-GEOD-14258 | biostudies-arrayexpress
TranscriptomicsRNA-seq of Candida albicans cells of the wildtype strain SC5314 and a sky2 deletion mutant grown on different carbon sources (glucose, malic acid, succinic acid)
RNA-sequencing was performed to investigate the role of the Candida albicans protein kinase Sky2 in metabolic adaptation to alternative carbon sources. The Candida albicans wildtype strain SC5314 and a sky2 deletion mutant were grown in medium with either glucose (3h), malic acid (6h) or succinic ac...
ORGANISM(S): Candida albicans 
2026-04-01 | E-MTAB-16222 | biostudies-arrayexpress
TranscriptomicsRegulation of efflux pump expression and drug resistance by the transcription factors Mrr1, Upc2, and Cap1 in Candida albicans
Constitutive overexpression of the Mdr1 efflux pump is an important mechanism of acquired drug resistance in the yeast Candida albicans. The zinc cluster transcription factor Mrr1 is a central regulator of MDR1 expression, but other transcription factors have also been implicated in MDR1 regulation....
ORGANISM(S): Candida albicans 
2011-07-01 | E-GEOD-23532 | biostudies-arrayexpress
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