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Genomicsp120 RasGAP and ZO-2 promote the tumor suppressor function of p190A RhoGAP
p120 RasGAP and ZO-2 promote the tumor suppressor function of p190A RhoGAP
PRJNA876272 | ENA
Transcriptomicsp120 RasGAP and ZO-2 promote the tumor suppressor function of p190A RhoGAP
ARHGAP35 encoding p190A RhoGAP (p190A) was identified by GWAS as a major human cancer gene. Our published studies have determined that p190A is a tumor suppressor that activates the canonical Hippo pathway. To elucidate how p190A signals in this context, we performed mass spectrometry to identify p1...
ORGANISM(S): Homo sapiens 
2023-04-15 | GSE212619 | GEO
ProteomicsSNX27 interactome during immune synapse formation
T lymphocyte recognition of antigenic peptides on the surface of antigen-presenting cells (APC) leads to immune synapse formation (IS). By analogy with the nervous synapse, this cell-cell communication model requires the formation of highly organized structures that delimit an active zone of membran...
ORGANISM(S): Homo sapiens (Human) 
2017-05-11 | PXD003628 | Pride
Snx27 Immune synapse Zo-2 T-lymphocyte Pdz 
UnknownDifferent effects of ZO-1, ZO-2 and ZO-3 silencing on kidney collecting duct principal cell proliferation and adhesion.
Not available
S-EPMC4612710 | biostudies-literature
UnknownZO-1- and ZO-2-dependent integration of myosin-2 to epithelial zonula adherens.
Not available
S-EPMC2526713 | biostudies-literature
UnknownMolecular alterations associated with pathophysiology in liver-specific ZO-1 and ZO-2 knockout mice.
Not available
S-EPMC11930773 | biostudies-literature
UnknownGNAQ-Regulated ZO-1 and ZO-2 Act as Tumor Suppressors by Modulating EMT Potential and Tumor-Repressive Microenvironment in Lung Cancer.
Not available
S-EPMC10218451 | biostudies-literature
UnknownAltered expression of ZO-1 and ZO-2 in Sertoli cells and loss of blood-testis barrier integrity in testicular carcinoma in situ.
Not available
S-EPMC1783719 | biostudies-literature
UnknownEarly embryonic lethality of mice lacking ZO-2, but Not ZO-3, reveals critical and nonredundant roles for individual zonula occludens proteins in mammalian development.
Not available
S-EPMC2258782 | biostudies-literature
UnknownTight junction protein ZO-2 modulates the nuclear accumulation of transcription factor TEAD.
Not available
S-EPMC8694039 | biostudies-literature
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