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ProteomicsSystematic characterization of 21 post-translational modification using synthetic peptides
The data presented in this study in the - context of the ProteoemTools project - is based on the synthesis of about 5000 synthetic peptides carrying 21 different post-translational modifications to systematically characterize their chromatographic and mass spectrometric properties using multimodal L...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-04-05 | MSV000091649 | MassIVE
ProteomicsProsit: Proteome-wide prediction of peptide tandem mass spectra by deep learning
In this study, we extended the ProteomeTools peptide library (PROPEL, see PXD004732 and PXD010595) to train a deep neural network resulting in chromatographic retention time and fragment ion intensity predictions for (tryptic) peptides that exceed the quality of the experimental data.
ORGANISM(S): Drosophila Melanogaster (ncbitaxon:7227) Escherichia Coli (ncbitaxon:562) Saccharomyces Cerevisiae (ncbitaxon:4932) Homo Sapiens (ncbitaxon:9606) Caenorhabditis Elegans (ncbitaxon:6239) 
2021-03-12 | MSV000087047 | MassIVE
ProteomicsProteomeTools â?? Part II - Prosit: proteome-wide prediction of peptide tandem mass spectra by deep learning
"The ProteomeTools project aims to derive molecular and digital tools from the human proteome to facilitate biomedical and life science research. Here, we describe the second iteration of the generation and multimodal LC-MS/MS analysis of >220,000 synthetic tryptic peptides representing nearly all c...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-07-21 | MSV000085805 | MassIVE
Proteomics,MultiomicsA deep proteome and transcriptome abundance atlas of 29 healthy human tissues
We generated a systematic, quantitative and deep proteome and transcriptome abundance atlas from 29 paired healthy human to serve as a molecular baseline to study human biology.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-03-02 | MSV000083508 | MassIVE
ProteomicsTarget Landscape of Clinical Kinase Inhibitors
Here, we provide a comprehensive overview of the selectivity profiles of 242 kinase inhibitors currently in clinical trials. We screened available inhibitors against human protein kinases by using the Kinobead technology resulting in a drug matrix identifying the druggable kinome and related protein...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-01-12 | MSV000081932 | MassIVE
ProteomicsH.sapiens - Placenta, SC (Wangetal,molsystbiol2019)
abundance based on Spectral counting, Interaction consistency score: 17.7, Coverage: 50
ORGANISM(S): 9606 
2019-00-00 | 408904952 | PAXDB
ProteomicsH.sapiens - Heart, SC (Wangetal,molsystbiol2019)
abundance based on Spectral counting, Interaction consistency score: 17.1, Coverage: 47
ORGANISM(S): 9606 
2019-00-00 | 2631912237 | PAXDB
ProteomicsH.sapiens - Lymph node, SC (Wangetal,molsystbiol2019)
abundance based on Spectral counting, Interaction consistency score: 17.0, Coverage: 48
ORGANISM(S): 9606 
2019-00-00 | 1105981147 | PAXDB
ProteomicsH.sapiens - Rectum, SC (Wangetal,molsystbiol2019)
abundance based on Spectral counting, Interaction consistency score: 17.4, Coverage: 50
ORGANISM(S): 9606 
2019-00-00 | 150411920 | PAXDB
ProteomicsH.sapiens - Colon, SC (Wangetal,molsystbiol2019)
abundance based on Spectral counting, Interaction consistency score: 15.9, Coverage: 51
ORGANISM(S): 9606 
2019-00-00 | 4014567567 | PAXDB
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