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TranscriptomicsHuman umbilical cord blood-derived endothelial colony forming cells under serum-free conditions
Derivation and expansion of human umbilical cord blood-derived endothelial colony forming cells under serum-free conditions - a transcriptome analysis. Endothelial colony forming cells (ECFCs) were isolated from term umbilical cord blood units. ECFCs were expanded under standard, fetal bovine serum ...
ORGANISM(S): Homo sapiens 
2010-07-29 | E-GEOD-20504 | biostudies-arrayexpress
TranscriptomicsTranscriptomic response to aluminum stress in roots of aspen (Populus tremula L.)
Background: Solubilized aluminum (Al) is rhizotoxic and can be present in acid soils at levels that inhibit root growth. Acid soils are found throughout the world and often support forests. However, unlike in herbaceous plants, little is known about the mechanisms by which forest trees respond to an...
ORGANISM(S): Populus tremula 
2010-08-24 | E-GEOD-19297 | biostudies-arrayexpress
TranscriptomicsMurine hepatocellular carcinoma of MCL1-/- transgenic mice and age matched alb cre mice - 12 months old.
aCGH analysis of murine transgenic liver tissues affected with HCC, hybridized with age (12 months) and sex matched alb cre mice. Keywords: Array comparative genomic hybridization analysis (aCGH). Independent HCC of MCL1-/- mice were hybridized with pooled wt mice. Mcl‑1flox/flox mice (C57BL/6 ba...
ORGANISM(S): Mus musculus 
2010-05-16 | E-GEOD-16580 | biostudies-arrayexpress
TranscriptomicsMurine hepatocellular carcinoma of AlbLTa/b transgenic mice and age matched C57BL/6 mice - 18 months old.
aCGH analysis of murine transgenic liver tissues affected with HCC, hybridized with age (18 months) and sex matched C57BL/6 mice. Moreover, 18months old C57BL/6 livers were hybridized with independent 18 months old C57BL/6 livers for control. Keywords: Array comparative genomic hybridization analy...
ORGANISM(S): Mus musculus 
2010-05-15 | E-GEOD-14467 | biostudies-arrayexpress
TranscriptomicsGlobal consequences of phosphatidylcholine reduction in Bradyrhizobium japonicum
Analysis of a Bradyrhizobium japonicum pmtA mutant. PmtA catalyzes the first of three consecutive methylation reactions leading to phosphatidylcholine (PC) formation in B. japonicum. Disruption of the pmtA gene results in a significantly reduced PC content causing a defect in symbiosis with the soyb...
ORGANISM(S): Bradyrhizobium japonicum 
2008-04-17 | E-GEOD-11187 | biostudies-arrayexpress
TranscriptomicsFunctional analysis of the cytoprotective transcription factor Nrf2 in skin morphogenesis and disease: Identification of Nrf2 target genes
The Nrf2 transcription factor is a key player in the cellular stress response, which regulates the expression of important antioxidant enzymes and other cytoprotective proteins. We recently generated a novel transgenic mouse model to determine the function of Nrf2 in the skin. These mice revealed in...
ORGANISM(S): Mus musculus 
2012-02-01 | E-GEOD-35160 | biostudies-arrayexpress
TranscriptomicsBone morphogenetic protein-7 is a MYC target with pro-survival functions in childhood medulloblastoma
Medulloblastoma (MB) is the most common malignant brain tumor in children, among whom overexpression or amplification of MYC oncogenes has been associated with poor clinical outcome. Although the MYC functions during normal development and oncogenesis in various systems have been extensively investi...
ORGANISM(S): Homo sapiens 
2011-05-16 | E-GEOD-22139 | biostudies-arrayexpress
UnknownOncogenic YAP sensitizes cells to CHK1 inhibition via CDK4/6 driven G1 acceleration
Not available
S-SCDT-10_1038-S44319-025-00514-5 | biostudies-other
TranscriptomicsComprehensive assessment of the regulons controlled by the FixLJ-FixK2-FixK1 cascade in Bradyrhizobium japonicum
Genome-wide transcription profiling of B. japonicum fixJ, fixK2, and fixK1 mutant strains which were grown in free-living microoxic condition, and in the case of the fixK1 mutant also in anoxic condition. Transcriptomes of nodules from soybean plants infected with the fixJ or fixK2 mutant strains we...
ORGANISM(S): Bradyrhizobium japonicum 
2010-05-23 | E-GEOD-12491 | biostudies-arrayexpress
UnknownDetailed stratified GWAS analysis for severe COVID-19 in four European populations.
Not available
S-EPMC9703941 | biostudies-literature
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