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ProteomicsFunctional analysis of Cdc20 reveals a critical role of CRY box in mitotic checkpoint signaling
Accurate chromosome segregation is coordinated by the spindle assembly checkpoint (SAC) through its effector the mitotic checkpoint complex (MCC), to inhibit the anaphase-promoting complex or cyclosome (APC/C). Cdc20 is an essential mitotic regulator since it promotes mitotic exit through activating...
ORGANISM(S): Homo sapiens (Human) 
2023-12-06 | PXD045411 | Pride
Cdc20 cry box crispr cas9 mitosis 
UnknownThe CRY box: a second APCcdh1-dependent degron in mammalian cdc20.
Not available
S-EPMC1618383 | biostudies-literature
TranscriptomicsTranscription profiling of livers from wild type, Clock mutant and Cry deficient C57BL/6 mice to characterize CLOCK-regulated circadian output genes.
Molecular analysis of circadian rhythm in mice. Liver tissue of wildtype, Clock mutant and Cry deficient C57BL/6 8- to 10-week-old male mice examined.
ORGANISM(S): Mus musculus 
2007-11-07 | E-GEOD-454 | biostudies-arrayexpress
ModelsAlmeida2019 - Transcription-based circadian mechanism controls the duration of molecular clock states in response to signaling inputs
This is a transcriptional-based mathematical model centered on linear combinations of the clock controlled elements (CCEs): E-box, R-box and D-box, used to identify the essential interactions needed to generate phase opposition between the activating CLOCK:BMAL1 and the repressing PER:CRY complexes.
2024-09-02 | BIOMD0000000839 | BioModels
UnknownFunctional analysis of Cdc20 reveals a critical role of CRY box in mitotic checkpoint signaling.
Not available
S-EPMC10858191 | biostudies-literature
TranscriptomicsCircadian rhythm in clock mutants
One hundred ninety wildtype male C57BL/6J mice age 7-10 weeks were purchased from Jackson Laboratory and entrained to a 12:12 light:dark cycle for 2 weeks. Mice were placed in light-tight boxes on a 12:12 LD cycle for 4 weeks, then released into constant darkness. Starting 30 hours after entry into ...
ORGANISM(S): Mus musculus 
2010-06-12 | E-GEOD-3751 | biostudies-arrayexpress
UnknownCompeting E3 ubiquitin ligases govern circadian periodicity by degradation of CRY in nucleus and cytoplasm.
Not available
S-EPMC3694781 | biostudies-literature
UnknownCircadian mutant Overtime reveals F-box protein FBXL3 regulation of cryptochrome and period gene expression.
Not available
S-EPMC3762874 | biostudies-literature
UnknownA Sextuple Knockout Cell Line System to Study the Differential Roles of CRY, PER, and NR1D in the Transcription-Translation Feedback Loop of the Circadian Clock.
Not available
S-EPMC7768009 | biostudies-literature
UnknownEvaluation of cytotoxic and antimicrobial effects of two Bt Cry proteins on a GMO safety perspective.
Not available
S-EPMC4140143 | biostudies-literature
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