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TranscriptomicsAnti-proliferative tumor suppressor-like activity of mir-9 overexpression and identification of novel mir-9 targets by trancription profiling in breast cancer cells
Investigation of genome-wide effects (transcriptome profiling) and direct targets of mir-9 in MCF-7 cells transfected with mir-9 in two dosages (1X and 2X) Following transfections of mir-9 or control miRNA mimics, total RNA was isolated and microarray profiling was performed.
ORGANISM(S): Homo sapiens 
2012-09-04 | E-GEOD-33952 | biostudies-arrayexpress
UnknownLong-term functioning status of COVID-19 survivors: a prospective observational evaluation of a cohort of patients surviving hospitalisation.

Objectives

The study investigated the long-term functional status of hospitalised COVID-19 survivors to explore and document their functional situation.

Design

This prospective observational study assessed 801 COVID-19 survivors at 3-11 months after hospital discharge. It analyses par...
S-EPMC9334693 | biostudies-literature
UnknownUbiquitin-specific proteases are differentially expressed throughout the Schistosoma mansoni life cycle.

Background

The ubiquitination process can be reversed by deubiquitinating enzymes (DUBs). These proteases are involved in ubiquitin processing, in the recovery of modified ubiquitin trapped in inactive forms, and in the recycling of ubiquitin monomers from polyubiquitinated chains. The diver...
S-EPMC4485857 | biostudies-literature
UnknownProtein-based tools for the detection and characterisation of Oropouche virus infection
Oropouche fever is a neglected tropical disease caused by the orthobunyavirus Oropouche virus (OROV). A recent OROV epidemic caused by a novel reassortant has seen infections across an expanded geographical range, with deaths of healthy adults plus vertical transmission leading to pregnancy loss. OR...
S-SCDT-10_1038-S44321-025-00291-7 | biostudies-other
UnknownInulin diet uncovers complex diet-microbiota-immune cell interactions remodeling the gut epithelium.

Background

The continuous proliferation of intestinal stem cells followed by their tightly regulated differentiation to epithelial cells is essential for the maintenance of the gut epithelial barrier and its functions. How these processes are tuned by diet and gut microbiome is an important,...
S-EPMC10131329 | biostudies-literature
UnknownEffect of Lung Recruitment and Titrated Positive End-Expiratory Pressure (PEEP) vs Low PEEP on Mortality in Patients With Acute Respiratory Distress Syndrome: A Randomized Clinical Trial.

Importance

The effects of recruitment maneuvers and positive end-expiratory pressure (PEEP) titration on clinical outcomes in patients with acute respiratory distress syndrome (ARDS) remain uncertain.

Objective

To determine if lung recruitment associated with PEEP titration according ...
S-EPMC5710484 | biostudies-literature
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