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MetabolomicsMacrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques
Macrophages represent a major immune cell population in atherosclerotic plaques and play central role in the progression of this lipid-driven chronic inflammatory disease. Targeting immunometabolism is proposed as a strategy to revert aberrant macrophage activation to improve disease outcome. Here, ...
2021-03-05 | MTBLS2159 | MetaboLights
Transcriptomicssingle cell RNA sequencing of 120h mouse gastruloids cultured with different doses of retinol
We quantified the effects of retinol on the cell type composition of gastruloids at 120 hours after aggregation by single cell RNA sequencing (scRNA-seq). Gastruloids were generated from the Rarb2.LacZ reporter cell line and cultured according to the standard protocol and few modifications: - cultu...
ORGANISM(S): Mus musculus 
2026-07-24 | E-MTAB-17398 | biostudies-arrayexpress
TranscriptomicsInvolvement of the TGF-β and β-catenin pathways in pelvic lymph node metastasis in early stage cervical cancer
Purpose: Presence of pelvic lymph node metastases is the main prognostic factor in early stage cervical cancer patients, primarily treated with surgery. Aim of this study was to identify cellular tumor pathways associated with pelvic lymph node metastasis in early stage cervical cancer. Experimental...
ORGANISM(S): Homo sapiens 
2011-02-15 | E-GEOD-26511 | biostudies-arrayexpress
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