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TranscriptomicsIdentification of genes essential for Moraxella catarrhalis growth under iron-limiting conditions using Genomic Array Footprinting (GAF): Expression analysis of directed gene deletion mutants.
Iron-sequestration by the human host is a first line defense against respiratory pathogens like Moraxella catarrhalis, which consequently experiences a period of iron-starvation during colonization and infection. We determined the genetic requirements for M. catarrhalis growth during iron-starvation...
ORGANISM(S): Moraxella catarrhalis BBH18 
2013-06-06 | E-GEOD-41547 | biostudies-arrayexpress
TranscriptomicsIdentification of genes essential for Moraxella catarrhalis growth under iron-limiting conditions using Genomic Array Footprinting (GAF)
Iron-sequestration by the human host is a first line defense against respiratory pathogens like Moraxella catarrhalis, which consequently experiences a period of iron-starvation during colonization and infection. We determined the genetic requirements for M. catarrhalis growth during iron-starvation...
ORGANISM(S): Moraxella catarrhalis BBH18 
2013-06-06 | E-GEOD-41546 | biostudies-arrayexpress
TranscriptomicsExpression profiling of Moraxella catarrhalis RH4 during in vitro growth in brain heart infusion (BHI) medium
Transcriptome analysis of M. catarrhalis RH4 predicted coding sequences and clustered regularly interspaced short palindromic repeats (CRISPRs) regions. The results described in this study are further discussed in De Vries, S.P.W., van Hijum, S.A.F.T., Schueler, W., Riesbeck, K., Hays, J.P., Hermans...
ORGANISM(S): Moraxella catarrhalis RH4 
2010-05-07 | E-GEOD-21632 | biostudies-arrayexpress
TranscriptomicsCharacterization of the molecular interplay between Moraxella catarrhalis and human respiratory tract epithelial cells: Expression response of human phanryngeal epithelial Detroit 562 cells to adherent Moraxella catarrhalis strain BBH18
During the course of infection, respiratory pathogens like Moraxella catarrhalis needs to adhere to epithelial cells of different host niches such as the nasopharynx and lungs. Consequently, efficient adhesion to epithelial cells is considered an important virulence trait of M. catarrhalis. We exam...
ORGANISM(S): Homo sapiens 
2013-06-27 | E-GEOD-47711 | biostudies-arrayexpress
TranscriptomicsCharacterization of the molecular interplay between Moraxella catarrhalis and human respiratory tract epithelial cells: Expression Moraxella catarrhalis strain BBH18 during adherence to human phanryngeal epithelial Detroit 562 cells
During the course of infection, respiratory pathogens like Moraxella catarrhalis needs to adhere to epithelial cells of different host niches such as the nasopharynx and lungs. Consequently, efficient adhesion to epithelial cells is considered an important virulence trait of M. catarrhalis. We exam...
ORGANISM(S): Moraxella catarrhalis 
2013-06-27 | E-GEOD-47870 | biostudies-arrayexpress
TranscriptomicsGene expression of non-typeable Haemophilus influenzae strain R2866 and R2866Δ0112 mutant grown in supplemented brain-heart infusion medium for 4 hours
Gene expresison profiles of the R2866 WT and R2866Δ0112 mutant gorwn 4 hours in supplemented brain-heart infusion medium. This experiment was conducted to determine the effects of R2866_0112 gene deletion on overall gene expression profile. The results from this study are further discussed in: Mod...
ORGANISM(S): Haemophilus influenzae R2866 
2013-12-13 | E-GEOD-53287 | biostudies-arrayexpress
TranscriptomicsGene expression of non-typeable Haemophilus influenzae strain R2866 and R2866Δ0112 mutant grown in supplemented brain-heart infusion medium for 7 hours
Gene expresison profiles of the R2866 WT and R2866Δ0112 mutant gorwn 7 hours in supplemented brain-heart infusion medium. This experiment was conducted to determine the effects of R2866_0112 gene deletion on overall gene expression profile. The results from this study are further discussed in: Mod...
ORGANISM(S): Haemophilus influenzae R2866 
2013-12-13 | E-GEOD-53289 | biostudies-arrayexpress
UnknownClinical management of chronic mesenteric ischemia.
Not available
S-EPMC6498801 | biostudies-literature
TranscriptomicsDeciphering the genetic basis of Moraxella catarrhalis complement resistance: Gene expression analysis of Moraxella catarrhalis BBH18 upon exposure to normal human serum.
The complement system is an important part of the innate defense against invading pathogens. The ability to resist complement-mediated killing is considered to be an important virulence trait for the human-restricted respiratory tract pathogen M. catarrhalis, as most disease-associated M. catarrhali...
ORGANISM(S): Moraxella catarrhalis BBH18 
2014-06-23 | E-GEOD-52552 | biostudies-arrayexpress
ProteomicsImmunopeptidomics analysis of human atherosclerosis plaques identifies antigenic drivers of atherosclerosis
Atherosclerosis has an auto-immune component driven by self-reactive T and B cells. Identifying their antigenic drivers may lead to new diagnosis and treatment approaches. Here, we aim to identify immunogenic T cell epitopes derived from atherosclerosis-relevant proteins such as ApoB100 by studying ...
ORGANISM(S): Homo sapiens (Human) 
2025-09-18 | PXD068446 | Pride
Immunopeptidomics Pbmcs Apob100 Antigen-specific t cells 
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