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TranscriptomicsDissecting modes of action of non-genotoxic carcinogens in primary mouse hepatocytes.
Under REACH, the European Community Regulation on chemicals, the testing strategy for carcinogenicity is generally based on in vitro and in vivo genotoxicity assays. Given that non-genotoxic carcinogens are negative for genotoxicity, this class of carcinogens will not be detected. Therefore, alterna...
ORGANISM(S): Mus musculus 
2012-06-25 | E-GEOD-35058 | biostudies-arrayexpress
TranscriptomicsMicroRNA and mRNA biomarkers for short-term in vivo genotoxic and non-genotoxic carcinogen classification
Many innovative techniques and scientific improvements are available to tackle societal concerns, like public health safety and confining the risk of cancerous exposure to chemicals, but have not been thoroughly tested and implicated yet. We investigated if microRNA and mRNA transcription profiles c...
ORGANISM(S): Mus musculus 
2014-04-01 | E-GEOD-43977 | biostudies-arrayexpress
TranscriptomicsMicroRNA and mRNA biomarkers for short-term in vivo genotoxic and non-genotoxic carcinogen classification
Many innovative techniques and scientific improvements are available to tackle societal concerns, like public health safety and confining the risk of cancerous exposure to chemicals, but have not been thoroughly tested and implicated yet. We investigated if microRNA and mRNA transcription profiles c...
ORGANISM(S): Mus musculus 
2014-04-01 | E-GEOD-43847 | biostudies-arrayexpress
UnknownThe Space Omics and Medical Atlas (SOMA) and international astronaut biobank.
Not available
S-EPMC11357981 | biostudies-literature
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