Sort   by:  
 Page size 
TranscriptomicsExpression data of CD4+T cells from Idiopathic CD4+ T cells lymphopenia (ICL) patients, Sarcoidosis (SARC) and Healthy individuals
This work focuses on understanding the molecular basis of the immune dysfunctions in Idiopathic CD4+ T cells lymphocytopenia (ICL). ICL is a rare haematological disorder of unknown origin, characterized by a profound and persistent CD4+ T-cell defect, which predisposes to life threatening opportunis...
ORGANISM(S): Homo sapiens 
2015-05-15 | E-GEOD-56998 | biostudies-arrayexpress
TranscriptomicsHuman induced pluripotent stem cells reveal early developmental molecular correlates with a probable Leber congenital amaurosis type I
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2015-01-21 | E-GEOD-43946 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression analysis of human iPSC-derived Retinal Pigmented Epithelial (RPE) cells from LCA patients and unaffected persons
Our purpose was to investigate genes and molecular mechanisms involved in patients with Leber congenital amaurosis (LCA). Fibroblasts from two unrelated clinically-identified patients (Coriell) were reprogrammed to pluripotency by retroviral transduction. These human induced Pluripotent Stem Cells (...
ORGANISM(S): Homo sapiens 
2015-01-21 | E-GEOD-43926 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression analysis of human iPSC-derived Neural Stem Cells (NSC) from LCA patients and unaffected persons
Our purpose was to investigate genes and molecular mechanisms involved in patients with Leber congenital amaurosis (LCA). Fibroblasts from two unrelated clinically-identified patients (Coriell) were reprogrammed to pluripotency by retroviral transduction. These human induced Pluripotent Stem Cells (...
ORGANISM(S): Homo sapiens 
2015-01-21 | E-GEOD-43924 | biostudies-arrayexpress
TranscriptomicsEffect of SRSF2 over-expression in a human lung carcinoma cell line
We showed that the over-expression of the SR protein SRSF2 led to the regulation of transcript abundance of many genes. H358 cell line with 6 samples with SRSF2 over-expression and 6 samples as control.
ORGANISM(S): Homo sapiens 
2013-08-30 | E-GEOD-50467 | biostudies-arrayexpress
TranscriptomicsExpression data from mouse perigonadal white adipose tissue - various mutant conditions [gene-level analysis]
Progerin-expressing mice (HGPS-like) demonstrated increased energy metabolism and lipodystrophy. Increased mitochondrial biogenesis was found in adipose tissue from HGPS-like mice, whereas lamin C-only mice had fewer mitochondria. Thus we analyse which molecular pathways mediated the changes in adip...
ORGANISM(S): Mus musculus 
2015-06-05 | E-GEOD-51202 | biostudies-arrayexpress
TranscriptomicsExpression data from mouse perigonadal white adipose tissue - various mutant conditions [exon-level analysis]
Progerin-expressing mice (HGPS-like) demonstrated increased energy metabolism and lipodystrophy. Increased mitochondrial biogenesis was found in adipose tissue from HGPS-like mice, whereas lamin C-only mice had fewer mitochondria. Thus we analyse which molecular pathways mediated the changes in adip...
ORGANISM(S): Mus musculus 
2015-06-05 | E-GEOD-51203 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of PDX models with acquired resistance to endocrine treatments
Acquired resistance to endocrine therapy occurs with high frequency in patients with luminal breast cancer (LBC). We report here the establishment of four patient-derived xenograft models of LBC with acquired resistance in vivo to tamoxifen and estrogen deprivation. CEL files represent expresison da...
ORGANISM(S): Homo sapiens 
2014-07-09 | E-GEOD-55561 | biostudies-arrayexpress
TranscriptomicsExpression data from mouse perigonadal white adipose tissue - various mutant conditions
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2015-06-05 | E-GEOD-51204 | biostudies-arrayexpress
TranscriptomicsABT-737 treatment induces regulation and activation of pathways implicated in cell survival, proliferation and stem cells in treated AML mice survival, proliferation and stem cells in treated AML mice
Myelodysplastic syndrome (MDS) transforms into an acute myelogenous leukemia (AML) with associated increased bone marrow blast infiltration. Using a transgenic mouse model, MRP8[NRASD12/hBCL-2], in which the NRAS:BCL-2 complex at the mitochondria induces MDS progressing to AML with dysplastic featur...
ORGANISM(S): Mus musculus 
2013-11-06 | E-GEOD-48601 | biostudies-arrayexpress
Sort   by:  
 Page size